Results 41 to 50 of about 599,586 (355)

Eletroforese capilar acoplada à espectrometria de massas (CE-MS): vinte anos de desenvolvimento Capillary electrophoresis coupled to mass spectrometry (CE-MS): twenty years of development

Química Nova, 2008
CE-MS has been increasingly used for analysis of a vast array of compounds. This article reviews the different electrophoretic modes, interfaces and mass analyzers that are commonly used in the CE-MS coupling, as well as the technique advantages and ...
Nilson Antonio Assunção, Etelvino José Henriques Bechara, Ana Valéria Colnaghi Simionato, Marina Franco Maggi Tavares, Emanuel Carrilho   +4 more
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Gut alterations in a chronic kidney disease rat model with diet‐induced vascular calcification

FEBS Open Bio, EarlyView.
Chronic kidney disease (CKD) patients often suffer from intestinal and/or mineral and bone disorders. Using a rat model, we showed that uremic vascular calcification is associated with gut barrier alterations (decreased gut mucus production and Nlrp6 gene expression, increased gut inflammation), and plasma retention of gut‐origin uremic toxins (indoxyl
Piotr Bartochowski, Irene Cortijo, Shruti Bhargava, Bernard Jover, Fabrice Raynaud, Juliana H Boukhaled, Anne‐Dominique Lajoix, Vera Jankowski, Joachim Jankowski, Magali Cordaillat‐Simmons, Àngel Argilés, Nathalie Gayrard, Flore Duranton, Jonas Laget   +13 more
wiley   +1 more source

Exploiting the formation of adducts in mobile phases with ammonium fluoride for the enhancement of annotation in liquid chromatography-high resolution mass spectrometry based lipidomics

Journal of Chromatography Open, 2021
Liquid Chromatography-High Resolution Mass Spectrometry (LC-HRMS) based lipidomics has become the most versatile analytical tool to discover and detect lipids using a non-targeted approach.
Carolina Gonzalez-Riano, Ana Gradillas, Coral Barbas   +2 more
doaj  

Comprehensive biothreat cluster identification by PCR/electrospray-ionization mass spectrometry. [PDF]

PLoS ONE, 2012
Technology for comprehensive identification of biothreats in environmental and clinical specimens is needed to protect citizens in the case of a biological attack.
Rangarajan Sampath, Niveen Mulholland, Lawrence B Blyn, Christian Massire, Chris A Whitehouse, Nicole Waybright, Courtney Harter, Joseph Bogan, Mary Sue Miranda, David Smith, Carson Baldwin, Mark Wolcott, David Norwood, Rachael Kreft, Mark Frinder, Robert Lovari, Irene Yasuda, Heather Matthews, Donna Toleno, Roberta Housley, David Duncan, Feng Li, Robin Warren, Mark W Eshoo, Thomas A Hall, Steven A Hofstadler, David J Ecker   +26 more
doaj   +1 more source

Electrospray Ionization Efficiency Is Dependent on Different Molecular Descriptors with Respect to Solvent pH and Instrumental Configuration

PLoS ONE, 2016
Over the past decades, electrospray ionization for mass spectrometry (ESI-MS) has become one of the most commonly employed techniques in analytical chemistry, mainly due to its broad applicability to polar and semipolar compounds and the superior ...
Andreas Kiontke, Ariana Oliveira-Birkmeier, A. Opitz, C. Birkemeyer   +3 more
semanticscholar   +1 more source

Colchicine Concentrations and Relationship With Colchicine Efficacy and Adverse Events: Post Hoc Analysis of a Randomized Clinical Trial of Colchicine for Gout Flare Prophylaxis

Arthritis Care &Research, EarlyView.
Objective Our objective was to examine the relationship between colchicine plasma concentrations and clinical and demographic factors and to determine the relationship between colchicine concentrations and colchicine efficacy and colchicine‐specific adverse events.
Lisa K. Stamp, Anne Horne, Borislav Mihov, Jill Drake, Janine Haslett, Peter Chapman, Daniel F. B. Wright, Christopher Frampton, Nicola Dalbeth   +8 more
wiley   +1 more source

Influence of Solvent Relative Permittivity in Swab Spray Mass Spectrometry

Molecules
The influence of solvent properties on ion generation by swab spray ionization was investigated. The ability of a variety of solvents of different relative permittivity, surface tension, and viscosity to form a stable and reproducible electrospray was ...
Thomas Michael Muggli, Stefan Schürch
doaj   +1 more source

Electrospray Ionization-Induced Protein Unfolding [PDF]

Journal of the American Society for Mass Spectrometry, 2012
Electrospray ionization mass spectrometry (ESI-MS) measurements were performed under a variety of solution conditions on a highly acidic sub-fragment (B3C) of the C-terminal carbohydrate-binding repeat region of Clostridium difficile toxin B, and two mutants (B4A and B4B) containing fewer acidic residues.
Luiz Eugenio, Kenneth K.-S. Ng, Margaret A. Johnson, Elena N. Kitova, John S. Klassen, Hong Lin   +5 more
openaire   +3 more sources

Removing Homocoupling Defects in Alkoxy/Alkyl‐PBTTT Enhances Polymer:Fullerene Co‐Crystal Formation and Stability

Advanced Functional Materials, EarlyView.
PBTTT‐OR‐R, a C14‐alkoxy/alkyl‐PBTTT polymer derivative, is of substantial interest for optoelectronics due to its specific fullerene intercalation behavior and enhanced charge‐transfer absorption. Comparing this polymer with (S) and without (O) homocoupling defects reveals that PBTTT‐OR‐R(O) forms stable co‐crystals with PC61BM, while PBTTT‐OR‐R(S ...
Zhen Liu, Jochen Vanderspikken, Paola Mantegazza, Stefania Moro, Mouna Hamid, Sigurd Mertens, Niko Van den Brande, Laurence Lutsen, Vincent Lemaur, David Beljonne, Giovanni Costantini, Koen Vandewal, Bruno Van Mele, Wouter Maes, Bart Goderis   +14 more
wiley   +1 more source