Results 41 to 50 of about 230,711 (334)

Implications of Matrix Effects in Quantitative HPLC/ESI-ToF-MS Analyses of Atmospheric Organic Aerosols

Proceedings, 2020
Matrix-induced signal suppression or enhancements are known phenomena in electrospray ionization mass spectrometry. Very few studies report on method development for organic aerosols analyses with the evaluation of the matrix effects.
Cornelia Amarandei, Romeo Iulian Olariu, Cecilia Arsene   +2 more
doaj   +1 more source

Recent developments in the rapid analysis of plants and tracking their bioactive constituents [PDF]

, 2009
Natural products chemistry has witnessed many new developments in the last 5 years like extractions with subcritical water and ionic liquids, LC/HRMS and LC/SPE/cryo-NMR, UHPLC, TLC/MS, MS-based preparative HPLC, comprehensive chromatography (GC × GC, LC
Beek, T.A., van, Claassen, F.W., Dapkevicius, A., Exarchou, V., Jeurissen, S.M.F., Klift, E.J.C., van der, Koleva, I., Tetala, K.K.R.   +7 more
core   +2 more sources

An Organic Chemist’s Guide to Electrospray Mass Spectrometric Structure Elucidation

Molecules, 2019
Tandem mass spectrometry is an important tool for structure elucidation of natural and synthetic organic products. Fragmentation of odd electron ions (OE+) generated by electron ionization (EI) was extensively studied in the last few decades, however ...
Arnold Steckel, Gitta Schlosser
doaj   +1 more source

Further characterization of glycine-containing microcystins from the McMurdo Dry Valleys of Antarctica [PDF]

, 2015
Microcystins are hepatotoxic cyclic peptides produced by several cyanobacterial genera worldwide. In 2008, our research group identified eight new glycine-containing microcystin congeners in two hydro-terrestrial mat samples from the McMurdo Dry Valleys ...
Cary, S. Craig, Hamilton, David P., Holland, Patrick T., Prinsep, Michèle R., Puddick, Jonathan, Wood, Susanna A.   +5 more
core   +3 more sources

Betalains and phenolic compounds of leaves and stems of Alternanthera brasiliana and Alternanthera tenella [PDF]

, 2018
Betacyanins and phenolic compounds from acetonitrile:acidified water extracts of Alternanthera brasiliana and Alternanthera tenella were characterized and quantified using a high-performance liquid chromatography system coupled with diode array and ...
Alvarez, I., De Ancos, B., Deladino, Lorena, Molina García, A. D., Schneider Teixeira, Aline, Sánchez Moreno, C.   +5 more
core   +1 more source

Some Thoughts on Electrospray Ionization Mechanisms

European Journal of Mass Spectrometry, 2011
Electrospray ionization (ESI) mechanisms are highly complex, due to a series of physical and chemical phenomena taking place on a complex system, as a solution is. In fact, even if the solution of an analyte in a protic medium can be considered at first sight to be a two-component system, the presence of solvent dissociation equilibria and the ...
Crotti S, Seraglia R, Traldi P
openaire   +5 more sources

Electrospray Ionization Mass Spectrometry: A Technique to Access the Information beyond the Molecular Weight of the Analyte

International Journal of Analytical Chemistry, 2012
The Electrospray Ionization (ESI) is a soft ionization technique extensively used for production of gas phase ions (without fragmentation) of thermally labile large supramolecules.
Shibdas Banerjee, Shyamalava Mazumdar
doaj   +1 more source

Applications of Direct Injection Soft Chemical Ionisation-Mass Spectrometry for the Detection of Pre-blast Smokeless Powder Organic Additives [PDF]

, 2019
Analysis of smokeless powders is of interest from forensics and security perspectives. This article reports the detection of smokeless powder organic additives (in their pre-detonation condition), namely the stabiliser diphenylamine and its derivatives 2-
A Jordan, A Zeichner, B Agarwal, B Gilbert-López, C Cruces-Blanco, C Shen, C West, CA Mayhew, CM Mahoney, D Laza, D-MK Dennis, E Bernal Morales, E Goudsmits, F Biasioli, F Li, G Scherperel, H Meng, H-h Meng, J Bueno, JJ Perez, JJ Perez, JL Thomas, KH Chang, KL Reese, M Joshi, M Joshi, M López-López, M López-López, M Mach, M Morelato, M Zhao, O Cascio, O Dalby, P Sulzer, P Sulzer, R González-Méndez, R González-Méndez, R González-Méndez, RV Taudte, S Jürschik, W Lindinger, WA MacCrehan, WA MacCrehan, Y Tong, Z Abrego, Z Wu   +45 more
core   +2 more sources

Electrospray Ionization-Induced Protein Unfolding [PDF]

Journal of the American Society for Mass Spectrometry, 2012
Electrospray ionization mass spectrometry (ESI-MS) measurements were performed under a variety of solution conditions on a highly acidic sub-fragment (B3C) of the C-terminal carbohydrate-binding repeat region of Clostridium difficile toxin B, and two mutants (B4A and B4B) containing fewer acidic residues.
Luiz Eugenio, Kenneth K.-S. Ng, Margaret A. Johnson, Elena N. Kitova, John S. Klassen, Hong Lin   +5 more
openaire   +3 more sources

Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase GES‐1 by enmetazobactam and tazobactam

FEBS Letters, EarlyView.
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer, Philip Hinchliffe, Marko Hanževački, Christopher R. Bethel, Catherine L. Tooke, Marc W. Van der Kamp, Krisztina M. Papp‐Wallace, Robert A. Bonomo, Stuart Shapiro, Adrian J. Mulholland, James Spencer   +10 more
wiley   +1 more source