Results 41 to 50 of about 718,278 (381)

Co-populated Conformational Ensembles of β(2)-Microglobulin Uncovered Quantitatively by Electrospray Ionization Mass Spectrometry [PDF]

, 2004
Ordered assembly of monomeric human β(2)-microglobulin (β(2)m) into amyloid fibrils is associated with the disorder hemodialysis-related amyloidosis. Previously, we have shown that under acidic conditions (pH
Bjorkman, Cech, Chiti, Chiti, Chowdhury, Dobo, Dobson, Esposito, Felitsyn, Fenn, Fenn, Floege, Ganem, Gejyo, Gejyo, Gorevic, Goto, Grandori, Grandori, Hill, Hoshino, Jones, Kad, Kad, Kaltashov, Karlsson, Katou, Khan, Konermann, Konermann, Kraulis, Mayer, McParland, McParland, Mirza, Morgan, Ohashi, Pitkanen, Robinson, Samalikova, Samalikova, Saper, Selkoe, Siuzdak, Smith, Wanker, Yamaguchi   +46 more
core   +1 more source

Fragmentation reactions using electrospray ionization mass spectrometry: an important tool for the structural elucidation and characterization of synthetic and natural products.

Natural product reports (Print), 2016
Over the last decade, the number of studies reporting the use of electrospray ionization mass spectrometry (ESI-MS) in combination with collision cells (or other activation methods) to promote fragmentation of synthetic and natural products for ...
D. Demarque, A. Crotti, R. Vessecchi, J. Lopes, N. Lopes   +4 more
semanticscholar   +1 more source

Mechanosensitive Self-Replication Driven by Self-Organization [PDF]

, 2010
Self-replicating molecules are likely to have played an important role in the origin of life, and a small number of fully synthetic self-replicators have already been described.
Belenguer, Ana M.,, Carnall, Jacqui M.A.,, Otto, Sijbren,, Peyralans, Jérôme J.-P.,, Stuart, Marc C.A.,, Waudby, Christopher A.,   +5 more
core   +6 more sources

MetFish: a Metabolomics Pipeline for Studying Microbial Communities in Chemically Extreme Environments

mSystems, 2021
The identification and accurate quantification of metabolites using electrospray ionization-mass spectrometry (ESI-MS) in hypersaline samples is a challenge due to matrix effects.
Chengdong Xu, Sneha P. Couvillion, Ryan L. Sontag, Nancy G. Isern, Yukari Maezato, Stephen R. Lindemann, Taniya Roy Chowdhury, Rui Zhao, Beau R. Morton, Rosalie K. Chu, Ronald J. Moore, Janet K. Jansson, Vanessa L. Bailey, Paula J. Mouser, Margaret F. Romine, James F. Fredrickson, Thomas O. Metz   +16 more
doaj   +1 more source

Mass Spectrometry in the Elucidation of the Glycoproteome of Bacterial Pathogens [PDF]

, 2010
Presently some three hundred post-translational modifications are known to occur in bacteria in vivo. Many of these modifications play critical roles in the regulation of proteins and control key biological processes.
Graham, Robert L. J., Hess, Sonja
core   +1 more source

Mechanistic investigation of ionization suppression in electrospray ionization

Journal of the American Society for Mass Spectrometry, 2000
We show results from experiments designed to determine the relative importance of gas phase processes and solution phase processes into ionization suppression observed in biological sample extracts. The data indicate that gas phase reactions leading to the loss of net charge on the analyte is not likely to be the most important process involved in ...
King, Richard, Bonfiglio, Ryan, Fernandez-Metzler, Carmen, Miller-Stein, Cynthia, Olah, Timothy   +4 more
openaire   +2 more sources

Electrospray ionization of copper—glycine solutions [PDF]

Journal of the American Society for Mass Spectrometry, 1996
We have characterized the electrospray ionization (ESI) spectra of mixtures of the 3d transition metal ion Cu(2+) with both a model amino acid (glycine) and a simple peptide system (glycylglycine). We found what appear to be two major classes of ions.
Xu, Yaodong, Zhang, Xin, Yergey, Alfred L.   +2 more
openaire   +2 more sources

Electrospray Ionization Mass Spectrometry: A Technique to Access the Information beyond the Molecular Weight of the Analyte

International Journal of Analytical Chemistry, 2012
The Electrospray Ionization (ESI) is a soft ionization technique extensively used for production of gas phase ions (without fragmentation) of thermally labile large supramolecules.
Shibdas Banerjee, Shyamalava Mazumdar
doaj   +1 more source

A tutorial in small molecule identification via electrospray ionization‐mass spectrometry: The practical art of structural elucidation

Mass spectrometry reviews (Print), 2017
The identification of unknown molecules has been one of the cornerstone applications of mass spectrometry for decades. This tutorial reviews the basics of the interpretation of electrospray ionization‐based MS and MS/MS spectra in order to identify small‐
Thomas de Vijlder, D. Valkenborg, F. Lemière, E. Romijn, K. Laukens, F. Cuyckens   +5 more
semanticscholar   +1 more source