Results 61 to 70 of about 682,349 (297)

A targeted mass spectrometric analysis of phosphatidylinositol phosphate species

Journal of Lipid Research, 2005
The development of a new mass spectrometric lipid profiling methodology permits the identification of cellular phosphatidylinositol monophosphate/phosphatidylinositol bisphosphate/phosphatidylinositol trisphosphate (PIP/PIP2/PIP3) species that includes ...
Stephen B. Milne, Pavlina T. Ivanova, Dianne DeCamp, Robert C. Hsueh, H. Alex Brown   +4 more
doaj   +1 more source

Analysis of heparin oligosaccharides by capillary electrophoresis-negative-ion electrospray ionization mass spectrometry

Analytical and Bioanalytical Chemistry, 2016
Most hyphenated analytical approaches that rely on liquid chromatography–MS require relatively long separation times, produce incomplete resolution of oligosaccharide mixtures, use eluents that are incompatible with electrospray ionization, or require ...
Lei-Chwen Lin, Xinyue Liu, Xinyue Liu, Fuming Zhang, Lianli Chi, I. Amster, F. Leach, Qiangwei Xia, R. Linhardt   +8 more
semanticscholar   +1 more source

Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy

Advanced Materials, EarlyView.
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla, Jacqueline J. Li, Qunzhou Zhang, Korey Patwari, Shihong Shi, Hannah M. Yamagata, Ryann A. Joseph, Briyanna N. Hymms, Sridatta V. Teerdhala, Emily Fitzgerald, Ori Z. Chalom, Kushol Gupta, Mohamad‐Gabriel Alameh, Drew Weissman, Anh D. Le, Michael J. Mitchell   +15 more
wiley   +1 more source

About the Electrospray Ionization Source in Mass Spectrometry: Electrochemistry and On-chip Reactions

CHIMIA, 2009
The present work shows that the electrochemical properties of electrospray ionization (ESI) can be used to add functions to the process. As example, we show how the choice of the electrode material can be used to study interactions between metal
Michel Prudent, Manuel Méndez, Christophe Roussel, Bin Su, Niels Lion, Joël S. Rossier, Hubert H. Girault   +6 more
doaj   +1 more source

A Dual‐Bioresponsive and Programmable Microneedle Matrix as a Bioinspired Coupler for Orchestrating Diabetic Bone Regeneration

Advanced Materials, EarlyView.
This project developed a smart bandage‐like patch (a microneedle array) for repairing diabetic bone damage. It intelligently senses signals from infection and inflammation, then releases its medicines in a specific, timed sequence: first an antibacterial agent, then an anti‐inflammatory agent, and finally growth factors.
Yu Wang, Rui Chen, Yu Chen, Haowen Lu, Yuchen Qian, Zhiheng Gao, Zheming Shen, Xiaofei Zheng, Huilin Yang, Jun Zou, Yusen Qiao   +10 more
wiley   +1 more source

Electrospray Ionization-Induced Protein Unfolding [PDF]

Journal of the American Society for Mass Spectrometry, 2012
Electrospray ionization mass spectrometry (ESI-MS) measurements were performed under a variety of solution conditions on a highly acidic sub-fragment (B3C) of the C-terminal carbohydrate-binding repeat region of Clostridium difficile toxin B, and two mutants (B4A and B4B) containing fewer acidic residues.
Hong, Lin, Elena N, Kitova, Margaret A, Johnson, Luiz, Eugenio, Kenneth K S, Ng, John S, Klassen   +5 more
openaire   +2 more sources

Correction: Taliaferro, L. et al. Evaluation of the Broad-Range PCR-Electrospray Ionization Mass Spectrometry (PCR/ESI-MS) System and Virus Microarrays for Virus Detection. Viruses 2014, 6, 1876-1896

Viruses, 2014
We have noted some inaccuracies in Table 1 and Table 2 of our article “Evaluation of the Broad-Range PCR-Electrospray Ionization Mass Spectrometry (PCR/ESI-MS) System and Virus Microarrays for Virus Detection” (Viruses 2014, 6, 1876–1896) [1].[...]
Lanyn P. Taliaferro, Teresa A. Galvin, Hailun Ma, Syed Shaheduzzaman, Dhanya K. Williams, Dustin R. Glasner, Arifa S. Khan   +6 more
doaj   +1 more source

Comprehensive biothreat cluster identification by PCR/electrospray-ionization mass spectrometry. [PDF]

PLoS ONE, 2012
Technology for comprehensive identification of biothreats in environmental and clinical specimens is needed to protect citizens in the case of a biological attack.
Rangarajan Sampath, Niveen Mulholland, Lawrence B Blyn, Christian Massire, Chris A Whitehouse, Nicole Waybright, Courtney Harter, Joseph Bogan, Mary Sue Miranda, David Smith, Carson Baldwin, Mark Wolcott, David Norwood, Rachael Kreft, Mark Frinder, Robert Lovari, Irene Yasuda, Heather Matthews, Donna Toleno, Roberta Housley, David Duncan, Feng Li, Robin Warren, Mark W Eshoo, Thomas A Hall, Steven A Hofstadler, David J Ecker   +26 more
doaj   +1 more source

On-Tissue Derivatization via Electrospray Deposition for Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging of Endogenous Fatty Acids in Rat Brain Tissues

Analytical Chemistry, 2016
Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) is used for the multiplex detection and characterization of diverse analytes over a wide mass range directly from tissues.
Qian Wu, Troy J. Comi, Bin Li, S. Rubakhin, J. Sweedler   +4 more
semanticscholar   +1 more source

Reprogramming the Immunosuppressive Microenvironment in Triple‐Negative Breast Cancer via FAP‐Targeted Nanoprobes for Multimodal Imaging and Photothermal Therapy

Advanced Materials, EarlyView.
Targeting cancer‐associated fibroblasts (CAFs) with fibroblast activation protein (FAP)‐directed nanoprobes for multimodal imaging and photothermal remodeling of the immunosuppressive microenvironment to enhance immunotherapy in triple‐negative breast cancer (TNBC).
Ling Zhan, Yanhong Chen, Jingjing Hu, Chunting Wang, Huanhuan Liu, Defan Yao, Dengbin Wang   +6 more
wiley   +1 more source