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Electrospray Ionization Mass Spectrometry: A Technique to Access the Information beyond the Molecular Weight of the Analyte [PDF]

open access: yesInternational Journal of Analytical Chemistry, 2012
The Electrospray Ionization (ESI) is a soft ionization technique extensively used for production of gas phase ions (without fragmentation) of thermally labile large supramolecules.
Shibdas Banerjee, Shyamalava Mazumdar
doaj   +5 more sources

Analysis of Oligonucleotides by Electrospray Ionization Mass Spectrometry [PDF]

open access: greenCurrent Protocols in Nucleic Acid Chemistry, 2000
AbstractBecause of the high molecular weights and thermal lability of biomolecules such as nucleic acids and protein, they can be difficult to analyze by mass spectrometry. Such analyses require a “soft” ionization method that is capable of generating intact molecular ions.
Polo, Lenore M., Limbach, Patrick A.
core   +6 more sources

Extractive electrospray ionization mass spectrometry for analytical evaluation and synthetic preparation of pharmaceutical chemicals [PDF]

open access: yesFrontiers in Pharmacology, 2023
Extraction electrospray ionization mass spectrometry (EESI-MS), due to the unique configuration of its ionization module, enables the effective ionization of trace molecules of interest in samples containing complex matrices with high sensitivity, high ...
Manman Qin   +9 more
doaj   +2 more sources

Spatially-resolved in vivo plant metabolomics by laser ablation-based mass spectrometry imaging (MSI) techniques: LDI-MSI and LAESI [PDF]

open access: yesFrontiers in Plant Science, 2015
This short review aims to summarize the current developments and applications of mass spectrometry-based methods for in situ profiling and imaging of plants with minimal or no sample pre-treatment or manipulation.
Aleš eSvatoš, Benjamin eBartels
doaj   +4 more sources

Analysis of inositol phosphate metabolism by capillary electrophoresis electrospray ionization mass spectrometry

open access: yesNature Communications, 2020
Myo-Inositol phosphates (InsPs) and pyrophosphates (PP-InsPs) are important second messengers but their analysis remains challenging. Here, the authors develop a capillary electrophoresis-mass spectrometry method for the identification and quantitation ...
Danye Qiu   +14 more
doaj   +2 more sources

Quantitative measurement of different ceramide species from crude cellular extracts by electrospray ionization tandem mass spectrometry (ESI-MS/MS) [PDF]

open access: hybridJournal of Lipid Research, 1999
Ceramide (CER) is an important signaling molecule involved in a variety of cellular processes, including differentiation, cell growth, and apoptosis.
G. Liebisch   +7 more
doaj   +2 more sources

Electrospray ionization mass spectrometry fingerprinting of propolis [PDF]

open access: yesThe Analyst, 2004
Crude ethanolic extracts of propolis, a natural resin, have been directly analysed using electrospray ionization mass (ESI-MS) and tandem mass spectrometry (ESI-MS/MS) in the negative ion mode. European, North American and African samples have been analyzed, but emphasis has been given to Brazilian propolis which displays diverse and region-dependent ...
Vassya Bankova   +6 more
openaire   +5 more sources

Mass recalibration for desorption electrospray ionization mass spectrometry imaging using endogenous reference ions [PDF]

open access: yesBMC Bioinformatics, 2022
Background Mass spectrometry imaging (MSI) data often consist of tens of thousands of mass spectra collected from a sample surface. During the time necessary to perform a single acquisition, it is likely that uncontrollable factors alter the validity of ...
Paolo Inglese   +4 more
doaj   +2 more sources

Probing metal ion binding and conformational properties of the colicin E9 endonuclease by electrospray ionization time‐of‐flight mass spectrometry [PDF]

open access: bronze, 2002
Nano-electrospray ionization time-of-flight mass spectrometry (ESI-MS) was used to study the conformational consequences of metal ion binding to the colicin E9 endonuclease (E9 DNase) by taking advantage of the unique capability of ESI-MS to allow ...
Ewald T.J. van den Bremer   +6 more
openalex   +5 more sources

Recent Applications of Ambient Ionization Mass Spectrometry for Environmental Pollutant Detection [PDF]

open access: yesZhipu Xuebao, 2023
Along with the industrial development and human society progress, large number of pollutants have been discharged to induce the environmental pollution, which have attracted global attentions.
QIN Jing-yi, OUYANG Jin, NA Na
doaj   +1 more source

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