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Extractive electrospray ionization mass spectrometry for analytical evaluation and synthetic preparation of pharmaceutical chemicals [PDF]

open access: yesFrontiers in Pharmacology, 2023
Extraction electrospray ionization mass spectrometry (EESI-MS), due to the unique configuration of its ionization module, enables the effective ionization of trace molecules of interest in samples containing complex matrices with high sensitivity, high ...
Manman Qin   +9 more
doaj   +2 more sources

Nanobubbles in Electrospray Ionization Mass Spectrometry. [PDF]

open access: yesAnal Chem
Nanobubbles (NBs) are very small gas-filled cavities in solvents, and when their sizes reach diameters around 200 nm, they remain in solution for extended periods of time, featuring special chemical and physical properties. Here, we investigate the application of NBs in electrospray ionization.
Joseph G, Binny B, Venter AR.
europepmc   +3 more sources

Analysis of Oligonucleotides by Electrospray Ionization Mass Spectrometry [PDF]

open access: greenCurrent Protocols in Nucleic Acid Chemistry, 2000
AbstractBecause of the high molecular weights and thermal lability of biomolecules such as nucleic acids and protein, they can be difficult to analyze by mass spectrometry. Such analyses require a “soft” ionization method that is capable of generating intact molecular ions.
Polo, Lenore M., Limbach, Patrick A.
openaire   +5 more sources

Quantitative measurement of different ceramide species from crude cellular extracts by electrospray ionization tandem mass spectrometry (ESI-MS/MS) [PDF]

open access: hybridJournal of Lipid Research, 1999
Ceramide (CER) is an important signaling molecule involved in a variety of cellular processes, including differentiation, cell growth, and apoptosis.
G. Liebisch   +7 more
doaj   +2 more sources

Probing metal ion binding and conformational properties of the colicin E9 endonuclease by electrospray ionization time-of-flight mass spectrometry [PDF]

open access: bronze, 2002
Nano-electrospray ionization time-of-flight mass spectrometry (ESI-MS) was used to study the conformational consequences of metal ion binding to the colicin E9 endonuclease (E9 DNase) by taking advantage of the unique capability of ESI-MS to allow ...
HECK, ALBERT J.R.   +6 more
core   +5 more sources

Recent Applications of Ambient Ionization Mass Spectrometry for Environmental Pollutant Detection [PDF]

open access: yesZhipu Xuebao, 2023
Along with the industrial development and human society progress, large number of pollutants have been discharged to induce the environmental pollution, which have attracted global attentions.
QIN Jing-yi, OUYANG Jin, NA Na
doaj   +1 more source

Enhancing Metabolomic Coverage in Positive Ionization Mode Using Dicationic Reagents by Infrared Matrix-Assisted Laser Desorption Electrospray Ionization

open access: yesMetabolites, 2021
Mass spectrometry imaging is a powerful tool to analyze a large number of metabolites with their spatial coordinates collected throughout the sample. However, the significant differences in ionization efficiency pose a big challenge to metabolomic mass ...
Ying Xi, David C. Muddiman
doaj   +1 more source

Implementation of a MS/MS database for isoquinoline alkaloids and other annonaceous metabolites

open access: yesScientific Data, 2022
Measurement(s) electrospray ionization Technology Type(s) Ultra High-performance Liquid Chromatography • Tandem Mass ...
Salemon Akpa Agnès   +12 more
doaj   +1 more source

Research Progress of Highly Selective Solid Substrate Electrospray Ionization Sources for Mass Spectrometry [PDF]

open access: yesZhipu Xuebao, 2022
Solid substrate electrospray mass spectrometry is an ambient mass spectrometry method that involves carrying, ionization and detection of the samples. This approach has a wide range of applications, and which is appropriate for rapid mass spectrometric ...
ZHANG Feng;MU Guo-dong;LIU Tong
doaj  

Desorption Electrospray Ionization (DESI) Mass Spectrometric Imaging of the Distribution of Rohitukine in the Seedling of Dysoxylum binectariferum Hook. F. [PDF]

open access: yesPLoS ONE, 2016
Ambient ionization mass spectrometric imaging of all parts of the seedling of Dysoxylum binectariferum Hook. f (Meliaceae) was performed to reconstruct the molecular distribution of rohitukine (Rh) and related compounds.
Patel Mohana Kumara   +5 more
doaj   +1 more source

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