Results 161 to 170 of about 439,053 (379)

Seminolipid and its precursor/degradative product, galactosylalkylacylglycerol, in the testis of saposin A- and prosaposin-deficient mice

open access: yesJournal of Lipid Research, 2003
Sphingolipid activator proteins (saposins A, B, C, and D) are derived from a common precursor protein (prosaposin) and specifically activate in vivo degradation of glycolipids with short carbohydrate chains.
Keiko Tadano-Aritomi   +4 more
doaj  

Multi‐Targeting Macrocyclic Peptides as Nanomolar Inhibitors of Self‐ and Cross‐Seeded Amyloid Self‐Assembly of α‐Synuclein

open access: yesAngewandte Chemie International Edition, EarlyView.
Cross‐seeding of α‐synuclein (αSyn) amyloid self‐assembly by islet amyloid polypeptide (IAPP) has been suggested to link type 2 diabetes to Parkinson's disease. Here we show that designed multi‐targeting macrocyclic peptides previously found to inhibit IAPP and/or Alzheimer's amyloid‐β peptide (Aβ40(42)) are nanomolar inhibitors of both self‐ and IAPP ...
Simon Hornung   +16 more
wiley   +1 more source

Gastrointestinal endogenous proteins as a source of bioactive peptides : Doctor of Philosophy in Nutritional Sciences at Riddet Institute, Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 2016
Gastrointestinal endogenous proteins (GEP) were investigated as a source of bioactive peptides. In silico and in vitro methods were used singly or in combination to study GEP-derived peptides after simulated digestion.
Acharya, Prasannalakshmi
core  

Competition Between One‐ and Two‐Electron Unimolecular Reactions of Late 3d‐Metal Complexes [(Me3SiCH2)nM]– (M = Fe, Co, Ni, Cu; n = 2 – 4)

open access: yesAngewandte Chemie International Edition, Accepted Article.
Although organometallic complexes of the late 3d elements are known to undergo both one‐ and two‐electron reactions, their relative propensities to do so remain poorly understood. To gain direct insight into the competition between these different pathways, we have analyzed the unimolecular gas‐phase reactivity of a series of well‐defined model ...
Torben Kühl   +3 more
wiley   +1 more source

Lipidomics of cellular and secreted phospholipids from differentiated human fetal type II alveolar epithelial cells

open access: yesJournal of Lipid Research, 2006
Maturation of fetal alveolar type II epithelial cells in utero is characterized by specific changes to lung surfactant phospholipids. Here, we quantified the effects of hormonal differentiation in vitro on the molecular specificity of cellular and ...
Anthony D. Postle   +6 more
doaj  

Home - About - Disclaimer - Privacy