Analysis of Oligonucleotides by Electrospray Ionization Mass Spectrometry [PDF]
Current Protocols in Nucleic Acid Chemistry, 2000 AbstractBecause of the high molecular weights and thermal lability of biomolecules such as nucleic acids and protein, they can be difficult to analyze by mass spectrometry. Such analyses require a “soft” ionization method that is capable of generating intact molecular ions.
Polo, Lenore M., Limbach, Patrick A.
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Probing metal ion binding and conformational properties of the colicin E9 endonuclease by electrospray ionization time-of-flight mass spectrometry [PDF]
, 2002 Nano-electrospray ionization time-of-flight mass spectrometry (ESI-MS) was used to study the conformational consequences of metal ion binding to the colicin E9 endonuclease (E9 DNase) by taking advantage of the unique capability of ESI-MS to allow ...
HECK, ALBERT J.R. +6 more
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Quantitative measurement of different ceramide species from crude cellular extracts by electrospray ionization tandem mass spectrometry (ESI-MS/MS) [PDF]
Journal of Lipid Research, 1999 Ceramide (CER) is an important signaling molecule involved in a variety of cellular processes, including differentiation, cell growth, and apoptosis.
G. Liebisch +7 more
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Advances in MALDI Mass Spectrometry Imaging Single Cell and Tissues
Frontiers in Chemistry, 2022 Compared with conventional optical microscopy techniques, mass spectrometry imaging (MSI) or imaging mass spectrometry (IMS) is a powerful, label-free analytical technique, which can sensitively and simultaneously detect, quantify, and map hundreds of ...
Xiaoping Zhu +6 more
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Desorption Electrospray Ionization-Mass Spectrometry of Proteins [PDF]
Analytical Chemistry, 2007 Desorption electrospray ionization-mass spectrometry (DESI-MS) was evaluated for the detection of proteins ranging in molecular mass from 12 to 66 kDa. Proteins were uniformly deposited on a solid surface without pretreatment and analyzed with a DESI source coupled to a quadrupole ion trap mass spectrometer.
Richard T. Mayer +4 more
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Applications of Tandem Mass Spectrometry (MS/MS) in Protein Analysis for Biomedical Research
Molecules, 2022 Mass Spectrometry (MS) allows the analysis of proteins and peptides through a variety of methods, such as Electrospray Ionization-Mass Spectrometry (ESI-MS) or Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry (MALDI-MS).
Anca-Narcisa Neagu +5 more
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Is Charge Reduction in ESI Really Necessary? [PDF]
, 2008 The technique of charge reduction electrospray mass spectrometry (CREMS), which can reduce the charge state complexity produced in electrospray ionization (ESI), is ...
Smith, Lloyd M.
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Structure elucidation of sildenafil analogues in herbal products. [PDF]
, 2004 The structure of unknown compounds present in herbal products was elucidated using liquid chromatography-electrospray ionization-mass spectrometry, direct-infusion electrospray ionization-mass spectrometry, and nuclear magnetic resonance.
Bakker, F +7 more
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Química Nova, 2012 Solutions of [hydroxy(tosyloxy)iodo]benzene (HTIB or Koser's reagent) in acetonitrile were analyzed using high resolution electrospray ionization mass spectrometry (ESI-MS) and electrospray ionization tandem mass spectrometry (ESI-MS/MS) under different ...
Ramon S. Vasconcelos +2 more
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False positives and the detection of cyclodextrin inclusion complexes by electrospray mass spectrometry [PDF]
, 1995 The results of previous works that have claimed to detect cyclodextrin inclusion complexes via the “soft” ionization technique of electrospray ionization mass spectrometry are revisited.
Cunniff, John B., Vouros, Paul
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