Results 261 to 270 of about 204,339 (353)

Repeated Intake of Grapefruit Juice Inhibits CYP2B6, CYP2C9, CYP2C19, and CYP3A4 while Lingonberry Powder Does Not Induce Major CYP Enzymes in Humans

Clinical Pharmacology &Therapeutics, EarlyView.
Grapefruit juice is a well‐established inhibitor of cytochrome P450 (CYP) 3A4, but its effects on other CYP enzymes or organic anion transporting polypeptides (OATPs) are not fully characterized in humans. Recently, lingonberry powder was shown to induce murine CYP enzymes. We investigated the effects of lingonberry powder and grapefruit juice on seven
Laura Aurinsalo, Outi Lapatto‐Reiniluoto, Mika Kurkela, Mikko Neuvonen, Eeva Moilanen, Mikko Niemi, Aleksi Tornio, Janne T. Backman   +7 more
wiley   +1 more source

Automated sample preparation for electrospray ionization mass spectrometry based on CLOCK-controlled autonomous centrifugal microfluidics. [PDF]

Biomed Microdevices
Futami M, Naito H, Ninomiya S, Chen LC, Iwano T, Yoshimura K, Ukita Y.   +6 more
europepmc   +1 more source

Untargeted Metabolomics Identifies N‐Lactoyl‐Amino Acids as Dose‐Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes

Clinical Pharmacology &Therapeutics, EarlyView.
Metformin is the most widely prescribed antidiabetic drug, yet adherence remains difficult to objectively assess. Using untargeted metabolomics and lipidomics, we analyzed plasma from 637 patients with type 2 diabetes (T2D) with confirmed metformin use and 143 nondiabetic controls, annotating 614 metabolites.
Tomas Cajka, Jiri Hricko, Lucie Rudl Kulhava, Michaela Paucova, Michaela Novakova, Veronika Hola, Stanislava Rakusanova, Oliver Fiehn, Vojtech Skop, Ivana Lankova, Iva Miskova, Terezie Pelikanova, Martin Haluzik   +12 more
wiley   +1 more source

Screening and Identification of Glyceollins and Their Metabolites by Electrospray Ionization Tandem Mass Spectrometry with Precursor Ion Scanning

, 2013
Syeda S. Quadri, Robert E. Stratford, Stephen M. Boué, Richard B. Cole   +3 more
openalex   +2 more sources

[Comprehensive analytical chemistry experiment： analysis of non-covalent interactions between double-stranded deoxyribonucleic acid and a natural drug by electrospray ionization mass spectrometry]. [PDF]

Se Pu
Ma L, Wang YH, Yuan YL, Wang SS.
europepmc   +1 more source

Rapid Identification of New Psychoactive Substances in Letters by LA‐APCI‐MS

Drug Testing and Analysis, EarlyView.
Laser ablation coupled to molecular mass spectrometry utilizing a modified atmospheric pressure chemical ionization source was used for the detection of synthetic cannabinoid receptor agonists in infused prison mail samples. ABSTRACT New psychoactive substances (NPS), especially synthetic cannabinoid receptor agonists (SCRA), are increasingly smuggled ...
Mark Wesner, Hannah Rämisch, Laura Besch, Johannes Schmeinck, Uwe Karst   +4 more
wiley   +1 more source

Real-Time Identification of Aerosol-Phase Carboxylic Acid Production Using Extractive Electrospray Ionization Mass Spectrometry. [PDF]

Environ Sci Technol
Surdu M, Top J, Yang B, Zhang J, Slowik JG, Prévôt ASH, Wang DS, El Haddad I, Bell DM.   +8 more
europepmc   +1 more source

Simulation of the Metabolism of New Psychoactive Substances Using Electrochemistry‐Mass Spectrometry: Introducing an Innovative Software Tool for Rapid Data Evaluation

Drug Testing and Analysis, EarlyView.
A novel software tool for the rapid and efficient simulation of the metabolism of new psychoactive substances was developed and applied to mimic the metabolism of the synthetic cannabinoid receptor agonist MDMB‐4en‐PINACA. ABSTRACT An innovative software tool for the rapid and efficient simulation of the metabolism of new psychoactive substances (NPS ...
Mark Wesner, Steffen Heuckeroth, Michael Pütz, Uwe Karst   +3 more
wiley   +1 more source

Imaging of triglycerides in tissues using nanospray desorption electrospray ionization (Nano-DESI) mass spectrometry

, 2019
Daisy Unsihuay, Jiamin Qiu, Sneha Swaroop, Konstantin O. Nagornov, Anton N. Kozhinov, Yury O. Tsybin, Shihuan Kuang, Julia Laskin   +7 more
openalex   +2 more sources

Hyphenation of microflow chromatography with electrospray ionization mass spectrometry for bioanalytical applications focusing on low molecular weight compounds: A tutorial review. [PDF]

Mass Spectrom Rev
Girel S, Meister I, Glauser G, Rudaz S.
europepmc   +1 more source