Results 31 to 40 of about 293,062 (392)

Degrees of freedom effect on fragmentation in tandem mass spectrometry of singly charged supramolecular aggregates of sodium sulfonates [PDF]

open access: yes, 2013
The characteristic collision energy (CCE) to obtain 50% fragmentation of positively and negatively single charged non-covalent clusters has been measured.
Bongiorno, David   +7 more
core   +2 more sources

Desorption Electrospray Ionization Mass Spectrometry Imaging of Proteins Directly from Biological Tissue Sections.

open access: yesAnalytical Chemistry, 2018
Analysis of large biomolecules including proteins has proven challenging using ambient ionization mass spectrometry imaging techniques. Here, we have successfully optimized desorption electrospray ionization mass spectrometry (DESI-MS) to detect intact ...
Kyana Y. Garza   +5 more
semanticscholar   +1 more source

Current developments in LC-MS for pharmaceutical analysis [PDF]

open access: yes, 2002
The current developments in liquid chromatography-mass spectrometry (LC-MS) and its applications to the analysis of pharmaceuticals are reviewed. Various mass spectrometric techniques, including electrospray and nanospray ionization, atmospheric pressure
Lim, Chang-Kee, Lord, Gwyn A.
core   +1 more source

Distinguishing malignant from benign microscopic skin lesions using desorption electrospray ionization mass spectrometry imaging

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance Timely detection of microscopic tumors is of utmost importance in cancer diagnostics. We show that desorption electrospray ionization mass spectrometry imaging (DESI-MSI) can successfully locate microscopic aggregates of a common skin cancer,
K. Margulis   +5 more
semanticscholar   +1 more source

Electrospray ionization mass spectrometry of

open access: yesJournal of the American Society for Mass Spectrometry, 2000
Lysoglycerophosphocholine lipids (lyso-GPC) are important intermediates in the synthesis and metabolism of glycerophosphocholine lipids which are major components of the cellular lipid bilayer. Significant differences in the collisional induced decomposition (CID) behavior were observed for each of the four different subtypes of lyso-GPC in both ...
Robert C. Murphy, Nona Khaselev
openaire   +3 more sources

Ionization and transmission efficiency in an electrospray ionization—mass spectrometry interface [PDF]

open access: yesJournal of the American Society for Mass Spectrometry, 2007
The ionization and transmission efficiencies of an electrospray ionization (ESI) interface were investigated to advance the understanding of how these factors affect mass spectrometry (MS) sensitivity. In addition, the effects of the ES emitter distance to the inlet, solution flow rate, and inlet temperature were characterized.
Jason S. Page   +3 more
openaire   +2 more sources

Mass recalibration for desorption electrospray ionization mass spectrometry imaging using endogenous reference ions

open access: yesBMC Bioinformatics, 2022
Background Mass spectrometry imaging (MSI) data often consist of tens of thousands of mass spectra collected from a sample surface. During the time necessary to perform a single acquisition, it is likely that uncontrollable factors alter the validity of ...
Paolo Inglese   +4 more
doaj   +1 more source

Recent advances in expanding the coverage of the lipidome [PDF]

open access: yes, 2017
The lipidome comprises a large array of molecules with diverse physicochemical properties. Lipids are structural components of cells, act as a source of energy, and function as signaling mediators.
Kamphorst, Jurre J., Tumanov, Sergey
core   +1 more source

Evaporation and Discharge Dynamics of Highly Charged Multicomponent Droplets Generated by Electrospray Ionization [PDF]

open access: yes, 2010
We investigate the Rayleigh discharge and evaporation dynamics of highly charged two-component droplets consisting principally of methanol with 2-methoxyethanol, tert-butanol, or m-nitrobenzyl alcohol.
Beauchamp, J. L., Grimm, Ronald L.
core   +1 more source

A tutorial in small molecule identification via electrospray ionization‐mass spectrometry: The practical art of structural elucidation

open access: yesMass spectrometry reviews (Print), 2017
The identification of unknown molecules has been one of the cornerstone applications of mass spectrometry for decades. This tutorial reviews the basics of the interpretation of electrospray ionization‐based MS and MS/MS spectra in order to identify small‐
Thomas de Vijlder   +5 more
semanticscholar   +1 more source

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