Quantification of sirolimus by liquid chromatography-tandem mass spectrometry using on-line solid-phase extraction [PDF]
Quantification of the new immunosuppressant sirolimus (syn. rapamycin; Rapamune((R))) in whole blood by chromatography is essential for its clinical use since no immunoassay is available although monitoring is mandatory.
Fleischer, Claudia+5 more
core +1 more source
This study describes a novel method for single-cell analysis and lipid profiling by combining drop-on-demand inkjet cell printing and probe electrospray ionization mass spectrometry (PESI-MS).
Fengming Chen+5 more
semanticscholar +1 more source
Mass Spectrometry in the Elucidation of the Glycoproteome of Bacterial Pathogens [PDF]
Presently some three hundred post-translational modifications are known to occur in bacteria in vivo. Many of these modifications play critical roles in the regulation of proteins and control key biological processes.
Graham, Robert L. J., Hess, Sonja
core +1 more source
Synchronized dual-polarity electrospray ionization mass spectrometry [PDF]
This work describes the synchronized dual-polarity (DP) electrospray ionization (ESI) method and demonstrates the first DP ESI mass spectra obtained using two mass spectrometers. Stable double Taylor cones were produced by applying two counter electric voltages with opposite polarities to one electrosprayer.
Ming-Chia Huang+4 more
openaire +3 more sources
Recent developments in the rapid analysis of plants and tracking their bioactive constituents [PDF]
Natural products chemistry has witnessed many new developments in the last 5 years like extractions with subcritical water and ionic liquids, LC/HRMS and LC/SPE/cryo-NMR, UHPLC, TLC/MS, MS-based preparative HPLC, comprehensive chromatography (GC × GC, LC
Beek, T.A., van+7 more
core +2 more sources
CE-MS has been increasingly used for analysis of a vast array of compounds. This article reviews the different electrophoretic modes, interfaces and mass analyzers that are commonly used in the CE-MS coupling, as well as the technique advantages and ...
Nilson Antonio Assunção+4 more
doaj +1 more source
Structural Plasticity and Noncovalent Substrate Binding in the GroEL Apical Domain. A study using electrospray ionization mass spectrometry and fluorescence binding studies [PDF]
Advances in understanding how GroEL binds to non-native proteins are reported. Conformational flexibility in the GroEL apical domain, which could account for the variety of substrates that GroEL binds, is illustrated by comparison of several independent ...
Adams+62 more
core +1 more source
Real-time breath analysis by high-resolution mass spectrometry (HRMS) is a promising method to noninvasively retrieve relevant biochemical information.
Jiafa Zeng+4 more
doaj +1 more source
Determination of parabens in human urine by liquid chromatography coupled with electrospray ionization tandem mass spectrometry [PDF]
A simple and sensitive method was developed for the simultaneous determination of methyl, ethyl,n-propyl,n-butyl, and benzyl parabens in human urine by liquid chromatography coupled with electrospray ionization tandem mass spectrometry (LC-ESI-MS/MS).
Fu, Jiamo+6 more
core +1 more source
A targeted mass spectrometric analysis of phosphatidylinositol phosphate species
The development of a new mass spectrometric lipid profiling methodology permits the identification of cellular phosphatidylinositol monophosphate/phosphatidylinositol bisphosphate/phosphatidylinositol trisphosphate (PIP/PIP2/PIP3) species that includes ...
Stephen B. Milne+4 more
doaj +1 more source