Results 41 to 50 of about 201,447 (356)

Ambient ionization mass spectrometry in brain cancer diagnosis

Journal of Mass Spectrometry and Advances in the Clinical Lab
Cancer is the second leading cause of death in the United States, and with ongoing population growth and aging, its annual incidence continues to rise. Glioma is a malignant tumor of the brain and central nervous system (CNS).
Mahdiyeh Shahi, R. Graham Cooks
doaj   +1 more source

A targeted mass spectrometric analysis of phosphatidylinositol phosphate species

Journal of Lipid Research, 2005
The development of a new mass spectrometric lipid profiling methodology permits the identification of cellular phosphatidylinositol monophosphate/phosphatidylinositol bisphosphate/phosphatidylinositol trisphosphate (PIP/PIP2/PIP3) species that includes ...
Stephen B. Milne, Pavlina T. Ivanova, Dianne DeCamp, Robert C. Hsueh, H. Alex Brown   +4 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Assignment of polymorphic species of insulin analogues in ion mobility mass spectroscopy

Data in Brief, 2017
Electrospray ionization – ion mobility spectrometry – mass spectrometry (ESI–IMS–MS) allows the identification of protein polymorphic distribution of protein conformers and oligomers.
Maely P. Fávero-Retto, Luiz Henrique Guerreiro, Cássio M. Pessanha, Leonardo C. Palmieri, Luís Maurício T.R. Lima   +4 more
doaj   +1 more source

A Non-Covalent Dimer Formation of Quaternary Ammonium Cation with Unusual Charge Neutralization in Electrospray-Ionization Mass Spectrometry

Molecules, 2021
Specific and nonspecific non-covalent molecular association of biomolecules is characteristic for electrospray-ionization mass spectrometry analysis of biomolecules.
Paulina Grocholska, Marta Kowalska, Robert Wieczorek, Remigiusz Bąchor   +3 more
doaj   +1 more source

Electrospray ionization tandem mass spectrometry of monoketone curcuminoids [PDF]

Rapid Communications in Mass Spectrometry, 2020
Rationale Although monoketone curcuminoids (MKCs) have been largely investigated due to their biological activities, data on the gas‐phase fragmentation reactions of protonated MKCs under collision‐induced dissociation (CID) conditions are still scarce.
Tatiana M. Vieira, Renato P. Orenha, Eduardo J. Crevelin, Saulo S.P. Furtado, Ricardo Vessecchi, Renato L.T. Parreira, Antônio E.M. Crotti   +6 more
openaire   +2 more sources

Quantification of voriconazole in plasma by liquid chromatography-tandem mass spectrometry [PDF]

, 2005
A convenient liquid chromatography-tandem mass spectrometry method for the quantification of the triazole antifungal agent voriconazole in plasma samples is described. Fenbuconazole is used as an internal standard.
Boyd, Denning, Dooley, Gage, Glasmacher, Hyland, Johnson, Keevil, Ozawa, Pennick, Potoski, Roffey, Stopher, Trifilio, Vogeser, Vogeser, Vogeser   +16 more
core   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

Advanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers, Maximilian Hausherr, Michel Lim, Karin Schork, Bilhan Karacora, Robin Grugel, Martin Eisenacher, Isabel Gil Aldea, Peter Riederer, Manfred Gerlach, Katrin Marcus   +10 more
wiley   +1 more source

Shotgun lipidomic analysis of chemically sulfated sterols compromises analytical sensitivity:Recommendation for large-scale global lipidome analysis [PDF]

, 2014
Shotgun lipidomics affords comprehensive and quantitative analysis of lipid species in cells and tissues at high-throughput [1 5]. The methodology is based on direct infusion of lipid extracts by electrospray ionization (ESI) combined with tandem mass ...
Casanovas, Albert, Ejsing, Christer S, Hannibal-Bach, Hans Kristian, Jensen, Ole Nørregaard   +3 more
core   +1 more source

Removing Homocoupling Defects in Alkoxy/Alkyl‐PBTTT Enhances Polymer:Fullerene Co‐Crystal Formation and Stability

Advanced Functional Materials, EarlyView.
PBTTT‐OR‐R, a C14‐alkoxy/alkyl‐PBTTT polymer derivative, is of substantial interest for optoelectronics due to its specific fullerene intercalation behavior and enhanced charge‐transfer absorption. Comparing this polymer with (S) and without (O) homocoupling defects reveals that PBTTT‐OR‐R(O) forms stable co‐crystals with PC61BM, while PBTTT‐OR‐R(S ...
Zhen Liu, Jochen Vanderspikken, Paola Mantegazza, Stefania Moro, Mouna Hamid, Sigurd Mertens, Niko Van den Brande, Laurence Lutsen, Vincent Lemaur, David Beljonne, Giovanni Costantini, Koen Vandewal, Bruno Van Mele, Wouter Maes, Bart Goderis   +14 more
wiley   +1 more source