Results 181 to 190 of about 776,948 (400)

Therapeutic Repair of Sperm Quality Decline Caused by Polytetrafluoroethylene

Advanced Science, EarlyView.
Exposure to PTFE (teflon), a commonly used microplastic in non‐stick cookware, significantly reduces sperm quality in both humans and mice. Specifically, PTFE induces the disruption of sperm cytoskeleton and F‐actin assembly through targeting SKAP2 in haploid spermatid.
Shiming Gan, Shumin Zhou, Jiaming Zhou, Guanghui Zhang, Jingshou Chen, Rui Liu, Kuan Sun, Sisi Li, Wenjing Xiong, Yujiao Wen, Jianzhong Sheng, Yu Zhang, Jingchao Ren, Youjiang Li, Hefeng Huang, Chen Zhang   +15 more
wiley   +1 more source

Selection of internal standards for accurate quantification of complex lipid species in biological extracts by electrospray ionization mass spectrometry-What, how and why?

Mass spectrometry reviews (Print), 2017
Miao Wang, Chunyan Wang, Xianlin Han
semanticscholar   +1 more source

Identification of the acid-induced degradation products of omeprazole and 5-hydroxyomeprazole by high resolution mass spectrometry [PDF]

, 2018
Aherne, Bahlmann, Boxall, Brenton, Bruni, Brändström, Brändström, Brändström, Cao, Halling-Sørensen, Heberer, Holčapek, Jones, Karni, Kind, Kümmerer, Lagerstrom, Lindberg, Lindberg, López-Serna, Makarov, Makarov, McLafferty, Olbe, Patiny, Schäfer, Stumpf, Watson, Weidolf   +28 more
core   +1 more source

Translation of a Human‐Based Malaria‐on‐a‐Chip Phenotypic Disease Model for In Vivo Applications

Advanced Science, EarlyView.
Inoculation of the Malaria‐on‐a‐Chip model with human erythrocytes infected with Plasmodium falciparum can support the entire intraerythrocytic lifecycle for 7 days in vitro. Utilizing this human‐based, serum‐free model provides an alternative to animal testing by introducing a human‐based, preclinical alternative for antimalarial therapeutic delivery.
Michael J. Rupar, Hannah M. Hanson, Brianna L. Botlick, Narasimhan Sriram, Stephanie Rogers, Justin Zuniga, Zhanhe Liu, Steven J. Trimmer, Joseph M. Ciurca, Christopher J. Long, Christopher W. McAleer, Stephan Schmidt, Paola Favuzza, Philip Lowe, Nathalie Gobeau, James J. Hickman   +15 more
wiley   +1 more source

Determination of the endogenous phosphorylation state of B‐50/GAP‐43 and neurogranin in different brain regions by electrospray mass spectrometry [PDF]

, 1996
Mónica Di Luca, Lucia Pastorino, Vittorio Raverdino, P.N.E. de Graan, Antonio Caputi, Willem Hendrik Gispen, Flaminio Cattabeni   +6 more
openalex   +1 more source

Intraoperative assessment of tumor margins during glioma resection by desorption electrospray ionization-mass spectrometry

Proceedings of the National Academy of Sciences of the United States of America, 2017
V. Pirro, Clint M. Alfaro, A. Jarmusch, E. Hattab, A. Cohen-Gadol, R. Cooks   +5 more
semanticscholar   +1 more source

ADAR1 as a Placental Innate Immune Rheostat Sustaining the Homeostatic Balance of Intrinsic Interferon Response at the Maternal‐Fetal Interface

Advanced Science, EarlyView.
This study reveals that ADAR1, an RNA‐editing enzyme, fine‐tunes immune responses in the placenta by preventing the accumulation of immunogenic double‐stranded RNAs (dsRNAs) from interferon‐stimulated genes. The loss of ADAR1 in the placenta leads to excessive interferon signaling restricted to the junctional zone, disrupting placental development and ...
Xiaogang Chen, Xiangchao Xu, Jiahao Chen, Huiru Zhang, Wanshan Zheng, Wenzhe Yu, Xiaoqian Hu, Bin Cao   +7 more
wiley   +1 more source

Contaminant inclusion into protein crystals analyzed by electrospray mass spectrometry and X‐ray crystallography [PDF]

, 1998
Juan Carlos Fontecilla‐Camps, Frédéric Halgand, Éric Forest, Joachim Hirschler   +3 more
openalex   +1 more source

Mortalin and PINK1/Parkin‐Mediated Mitophagy Represent Ovarian Cancer‐Selective Targets for Drug Development

Advanced Science, EarlyView.
Ovarian cancer patients with high levels of mortalin protein in their tumors have worse survival. The investigational drug SHetA2 interferes with mortalin's support of mitochondria. The resulting mitochondrial damage causes a process called mitophagy that contributes to how SHetA2 kills cancer cells. Noncancerous cells repair their mitochondria through
Vishal Chandra, Justin Garland, Rajani Rai, Donghua Zhao, Charuksha Walgama, Sadagopan Krishnan, Andrew T. Long, Tongzu Liu, Laura Adhikari, Doris M. Benbrook   +9 more
wiley   +1 more source

Mass spectrometry of large organic ions by electrospray, particle and photon induced desorption: foreword [PDF]

, 1999
E. F. da Silveira
openalex   +1 more source