Results 241 to 250 of about 776,948 (400)

Cucurbit[7]Uril‐Based Supramolecular Polymers With Dual Photochromism and Fluorescence: From Host‒Guest Design to Smart Applications

open access: yesAggregate, EarlyView.
The supramolecular complexes of cucurbit[7]uril with thiophene‐pyridinium guests formed by different assembly ratios exhibit different photochromic and fluorescence properties, which render them suitable for applications in multi‐level anti‐counterfeiting and advanced information encryption.
Long‐Jing Wu   +5 more
wiley   +1 more source

Reduced Pressure Ionization Enhances Native Mass Spectrometry of Proteins and Protein Complexes

open access: yesAngewandte Chemie, EarlyView.
Reduced pressure for electrospray ionization of native proteins narrows peak widths and increases signal. This straightforward add‐on to existing native MS platforms improves performance in challenging buffers and enables detection of protein interactions at concentrations as low as 50 nM, without significantly disrupting structure as confirmed by ...
Jake P. Violi   +2 more
wiley   +2 more sources

The Synthesis of Nonsymmetric α‐hydroxy‐ethylidenebisphosphonic Derivatives by the Pudovik Reaction, Their Reactions, and Cytotoxic Activity

open access: yesAsian Journal of Organic Chemistry, EarlyView.
Nonsymmetric α‐hydroxy‐ethylidenebisphosphonates (HEBPs) are synthesized by the Pudovik reaction of dialkyl α‐oxo‐ethylphosphonates and P‐reagents (such as dialkyl phosphites, alkyl phenyl‐H‐phosphinates or diarylphosphine oxides). In the presence of 40% diethylamine, the primary adducts rearrange to the corresponding phosphonoyl‐phosphonate and ...
Zsuzsanna Szalai   +8 more
wiley   +1 more source

Hinge‐Like Mechanochromic Mechanophores Based on [2.2]Paracyclophane

open access: yesAngewandte Chemie, EarlyView.
Hinge‐like supramolecular mechanophores utilizing [2.2]paracyclophane have been developed. In the force‐free state, the rigid [2.2]paracyclophane forces two luminophores into proximity, leading to excimer‐dominant photoluminescence. Stretching the polyurethane films into which the mechanophores are covalently incorporated results in the structures of ...
Shohei Shimizu   +3 more
wiley   +2 more sources

Development, validation, and preliminary phenotypic characterization of a Col6a3 knockout mouse model targeting exon 3

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Deleting Col6a3 exon 3 by CRISPR in mice results in centralized nuclei consistent with a myopathy phenotype mimicking collagen VI‐associated human disease Abstract Background Most mutations in the COL6A3 gene lead to collagen VI‐related myopathies. This is due to a reduced expression or mislocalization of the COL6A3 protein.
Michel ElChoueiry   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy