Optimized Machine Learning for Autonomous Enzymatic Reaction Intensification in a Self‐Driving Lab
A machine learning‐powered self‐driving lab accelerates enzymatic reaction optimization by autonomously navigating complex parameter spaces. Through over 10,000 simulated campaigns, we identified an optimal algorithm for efficient, automated optimization.
Sebastian Putz+5 more
wiley +1 more source
Real-time capture of reactive intermediates in an enzymatic reaction: insights into a P450-catalyzed oxidation. [PDF]
Pahchan P+3 more
europepmc +1 more source
Synthetic organic dyes in documents were screened using online nonaqueous capillary electrophoresis–mass spectrometry. Abstract The increasing sophistication of handwriting forgery techniques highlights the need for reliable document authentication methods.
Joon Yub Kwon+2 more
wiley +1 more source
Unravelling lipid heterogeneity: Advances in single-cell lipidomics in cellular metabolism and disease. [PDF]
Sarkar S, Ghosh R.
europepmc +1 more source
A lipid droplet‐selective fluorescent probe for real‐time imaging and polarity sensing
In this study, we present a fluorescent probe 1 with lipid droplets‐targeting and solvent‐dependent emission properties. Its photophysical behavior and selectivity were analyzed using density functional theory (DFT), time‐dependent DFT, and confocal laser scanning microscopy.
Yerim Lee+5 more
wiley +1 more source
Critical Role of Voltage Application Points in "Analog" and "Digital" Electrospray Ionization Mass Spectrometry. [PDF]
Hung MM, Elpa DP, Ochirov O, Urban PL.
europepmc +1 more source
THF leverages a dual mechanism combining “low‐binding‐energy‐induced anion aggregate formation” and “weak‐interaction‐mediated reduction of ion migration energy barriers” to synergistically achieve stabilized interfacial architectures and enhanced ionic conductivity, presenting a novel paradigm for designing advanced batteries.
Xiaojuan Zhang+9 more
wiley +1 more source
Liquid chromatography-mass spectrometry approach for characterizing sucrose isomers in complex mono-floral honey. [PDF]
Amoah E+3 more
europepmc +1 more source
ABSTRACT Chemical investigation of Disynaphia filifolia (Hassl.) R.M. King & H. Rob. (Asteraceae) led to the isolation of eight compounds, with tremetone being the major metabolite recovered. Tremetone has been suggested as the toxic compound in Ageratina altissima and Isocoma pluriflora, two species of the Asteraceae family. Although D.
Yasmin Rodrigues Chierici+11 more
wiley +1 more source
Advances and Challenges in Structural Studies of Bioactive Peptide-Anthracycline Conjugates: A Mass Spectrometric Insight. [PDF]
Fehérvári E, Uray K, Schlosser G.
europepmc +1 more source