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The application of mass spectrometry imaging in traditional Chinese medicine: a review
Mass spectrometry imaging is a frontier technique which connects classical mass spectrometry with ion imaging. Various types of chemicals could be visualized in their native tissues using mass spectrometry imaging.
Lieyan Huang+7 more
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Mass spectrometry imaging is a powerful tool to analyze a large number of metabolites with their spatial coordinates collected throughout the sample. However, the significant differences in ionization efficiency pose a big challenge to metabolomic mass ...
Ying Xi, David C. Muddiman
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Over the last decade, the number of studies reporting the use of electrospray ionization mass spectrometry (ESI-MS) in combination with collision cells (or other activation methods) to promote fragmentation of synthetic and natural products for ...
D. Demarque+4 more
semanticscholar +1 more source
Model mass spectrometric study of competitive interactions of antimicrobial bisquaternary ammonium drugs and aspirin with membrane phospholipids [PDF]
The aim of the study is to reveal molecular mechanisms of possible activity modulation of antimicrobial bis-quaternary ammonium compounds (BQAC) and aspirin (ASP) through noncovalent competitive complexation under their combined introduction into the ...
Gömöry, Ágnes+3 more
core +2 more sources
Electrospray and tandem mass spectrometry in biochemistry [PDF]
Over the last 20 years, biological MS has changed out of all recognition. This is primarily due to the development in the 1980s of ‘soft ionization’ methods that permit the ionization and vaporization of large, polar, and thermally labile biomolecules.
Yuqin Wang+4 more
openaire +3 more sources
Sphingolipid activator proteins (saposins A, B, C, and D) are derived from a common precursor protein (prosaposin) and specifically activate in vivo degradation of glycolipids with short carbohydrate chains.
Keiko Tadano-Aritomi+4 more
doaj +1 more source
Measurement(s) Genome • Proteomic Profile Technology Type(s) PacBio Sequel System • nanoflow liquid chromatography-electrospray ionisation mass spectrometry Sample Characteristic - Organism Halomonas sp ...
Matthew Russell+5 more
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High throughput analysis is increasingly relevant in both industry and academia, with applications reaching from enzymology and drug discovery to organic reaction optimization and diagnostics.
Nicolás M. Morato, R. Graham Cooks
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The identification of unknown molecules has been one of the cornerstone applications of mass spectrometry for decades. This tutorial reviews the basics of the interpretation of electrospray ionization‐based MS and MS/MS spectra in order to identify small‐
Thomas de Vijlder+5 more
semanticscholar +1 more source
Newborn Sickle Cell Disease Screening Using Electrospray Tandem Mass Spectrometry
There is a growing demand for newborn sickle cell disease screening globally. Historically techniques have relied on the separation of intact haemoglobin tetramers using electrophoretic or liquid chromatography techniques.
Yvonne Daniel, Charles Turner
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