Measurement(s) Genome • Proteomic Profile Technology Type(s) PacBio Sequel System • nanoflow liquid chromatography-electrospray ionisation mass spectrometry Sample Characteristic - Organism Halomonas sp ...
Matthew Russell +5 more
doaj +1 more source
High throughput analysis is increasingly relevant in both industry and academia, with applications reaching from enzymology and drug discovery to organic reaction optimization and diagnostics.
Nicolás M. Morato, R. Graham Cooks
doaj +1 more source
Single-Cell Analysis and Its Applications by Surface Desorption Ambient Mass Spectrometry
As the fundamental units of the structure and function of living organisms, cells perform the core functions of life activities. With the deepening research in life sciences, the importance of studies on cellular heterogeneity has become increasingly ...
Dan LIN +5 more
doaj +1 more source
Mass spectrometry-directed synthesis of early–late sulfide-bridged heterobimetallic complexes from the metalloligand [Pt₂(PPh₃)₄(μ-S)₂] and oxo compounds of vanadium(V), molybdenum(VI) and uranium(VI) [PDF]
The metalloligand [Pt₂(PPh₃)₄(μ-S)₂] has been found to react with the transition metal oxo compounds, ammonium metavanadate, sodium molybdate, and the actinide complex uranyl nitrate to give sulfide-bridged heterobimetallic complexes [Pt₂(PPh₃)₄(μ₃-S)₂VO(
Fong, S.W. Audi +4 more
core +2 more sources
Structure elucidation of sildenafil analogues in herbal products. [PDF]
The structure of unknown compounds present in herbal products was elucidated using liquid chromatography-electrospray ionization-mass spectrometry, direct-infusion electrospray ionization-mass spectrometry, and nuclear magnetic resonance.
Bakker, F +7 more
core +1 more source
Generic sample preparation combined with high-resolution liquid chromatography- time-of-flight mass spectrometry for unification of urine screening in doping-control laboratories [PDF]
A unification of doping-control screening procedures of prohibited small molecule substances—including stimulants, narcotics, steroids, ß2-agonists and diuretics—is highly urgent in order to free resources for new classes such as banned proteins ...
Georgakopoulos, C.G. +4 more
core +3 more sources
Further characterization of glycine-containing microcystins from the McMurdo Dry Valleys of Antarctica [PDF]
Microcystins are hepatotoxic cyclic peptides produced by several cyanobacterial genera worldwide. In 2008, our research group identified eight new glycine-containing microcystin congeners in two hydro-terrestrial mat samples from the McMurdo Dry Valleys ...
Cary, S. Craig +5 more
core +3 more sources
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
CE-MS has been increasingly used for analysis of a vast array of compounds. This article reviews the different electrophoretic modes, interfaces and mass analyzers that are commonly used in the CE-MS coupling, as well as the technique advantages and ...
Nilson Antonio Assunção +4 more
doaj +1 more source
Multiplierz: An Extensible API Based Desktop Environment for Proteomics Data Analysis [PDF]
BACKGROUND. Efficient analysis of results from mass spectrometry-based proteomics experiments requires access to disparate data types, including native mass spectrometry files, output from algorithms that assign peptide sequence to MS/MS spectra, and ...
Askenazi, Manor +7 more
core +4 more sources

