Results 41 to 50 of about 58,413 (257)

AC Dual Excitation Multiphase Electrostatic Drive.

open access: yesJournal of the Robotics Society of Japan, 1997
An electrostatic motor technology that makes it possible to actuate machines with normal dimensions (not micro machines) by electrostatic force is developed. The novel motor is named AC Dual Excitation Multiphase Electrostatic Drive (ADEMED). It consists of a pair of two thin plastic films, called slider and stator, in both of which 3-phase parallel ...
Niino, Toshiki   +2 more
openaire   +2 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A highly efficient surface plasmon polaritons excitation achieved with a metal-coupled metal-insulator-metal waveguide

open access: yesAIP Advances, 2014
We propose a novel metal-coupled metal-insulator-metal (MC-MIM) waveguide which can achieve a highly efficient surface plasmon polaritons (SPPs) excitation. The MC-MIM waveguide is formed by inserting a thin metal film in the insulator of an MIM.
Hongyan Yang, Jianqing Li, Gongli Xiao
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Dynamic Characteristics of Microring Driven by the Symmetrically Distributed Electrostatic Force

open access: yesComplexity, 2021
This paper aims at investigating the dynamic characteristics of a microring driven by dual arch electrodes because they are basic elements of microelectrostatic motors.
Qingheng Meng   +5 more
doaj   +1 more source

Density functional theory studies on molecular structure, vibrational spectra, AIM, HOMO-LUMO, electronic properties, and NBO analysis of benzoic acid monomer and dimer

open access: yesVietnam Journal of Science, Technology and Engineering, 2023
In this study, the molecular structure, vibrational frequencies, and atom-in-molecule (AIM) analysis of the benzoic acid monomer and dimer were investigated.
Tan Trung Truong   +4 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

High-speed propulsion of magnetoelectric nanovehicle actuated by bio-cellular electric field sensing

open access: yesSensing and Bio-Sensing Research, 2022
We have demonstrated and experimentally verified a nanovehicle which exhibits magnetoelectric phenomenon and provides a swift cell targeting technique.
Soutik Betal   +2 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

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