Results 41 to 50 of about 60,457 (299)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
AC Dual Excitation Multiphase Electrostatic Drive.
Journal of the Robotics Society of Japan, 1997 An electrostatic motor technology that makes it possible to actuate machines with normal dimensions (not micro machines) by electrostatic force is developed. The novel motor is named AC Dual Excitation Multiphase Electrostatic Drive (ADEMED). It consists of a pair of two thin plastic films, called slider and stator, in both of which 3-phase parallel ...
Niino, Toshiki +2 more
openaire +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Using electrostatic nonlinearities to enhance the performance of ring-based Coriolis vibratory gyroscopes [PDF]
, 2023 This research investigates electrostatic nonlinearities in capacitively operated ring-based Coriolis vibrating gyroscopes (CVG’s). Large amplitude vibrations of the ring amplify the Coriolis force and are beneficial to achieving high-precision rate ...
Arifin, Davin
core +2 more sources
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Can the Thermodynamic Hodgkin-Huxley Model of Voltage-Dependent Conductance Extrapolate for Temperature? [PDF]
, 2014 Hodgkin and Huxley (H-H) fitted their model of voltage-dependent conductances to experimental data using empirical functions of voltage. The thermodynamic H-H model of voltage dependent conductances is more physically plausible, as it constrains and ...
Michael D. Forrest +2 more
core +1 more source
AIP Advances, 2014 We propose a novel metal-coupled metal-insulator-metal (MC-MIM) waveguide which can achieve a highly efficient surface plasmon polaritons (SPPs) excitation. The MC-MIM waveguide is formed by inserting a thin metal film in the insulator of an MIM.
Hongyan Yang, Jianqing Li, Gongli Xiao
doaj +1 more source
Vietnam Journal of Science, Technology and Engineering, 2023 In this study, the molecular structure, vibrational frequencies, and atom-in-molecule (AIM) analysis of the benzoic acid monomer and dimer were investigated.
Tan Trung Truong +4 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source