Results 101 to 110 of about 4,727,754 (333)
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
This study introduces an innovative model-order reduction (MOR) technique that integrates boundary element and finite element methodologies, streamlining the analysis of wideband vibro-acoustic interactions within aquatic and aerial environments.
Yanming Xu +3 more
doaj +1 more source
Vanishing elements of prime power order
An element $x$ in a finite group $G$ is said to be \textit{vanishing} if some (complex) irreducible character of $G$ takes value $0$ at $x$. In this article, we prove that every non-abelian finite simple group, except $\mathrm{SL}_2(4)$ and $\mathrm{SL}_2(8)$, contains a vanishing element \textit{of prime power order} whose conjugacy class size is ...
Arora, Sonakshee +1 more
openaire +2 more sources
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Products of elements of even order
It is known that the product of two non-conjugate elements of order two in a finite group has even order. In the paper under review, the author generalizes this result for the product of two suitable elements of even order. The following consequence (Corollary) is evident from the main result (Theorem 1): Suppose \(u\) and \(v\) are involutions in a ...
openaire +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Determination of the top-quark mass from top-quark pair events with the matrix element method at next-to-leading order: Potential and prospects [PDF]
Till Martini +2 more
openalex +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Optimally accurate higher-order finite element methods for polytopial approximations of domains with smooth boundaries [PDF]
James Chung‐Wai Cheung +3 more
openalex +1 more source

