Results 61 to 70 of about 223,481 (318)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

PENINGKATAN KOMPETENSI MENYUSUN RPP DAN MELAKSANAKAN PEMBELAJARAN MELALUI SUPERVISI AKADEMIK DENGAN TEKNIK OBSERVASI KELAS BAGI GURU SD NEGERI I BATURETNO

Elementary School, 2020
This study aims to improve the competency of preparing lesson plans and implementing learning through academic supervision with classroom observation techniques for teachers of SD Negeri I Baturetno in the 2018/2019 academic year.
Suyatmini Suyatmini
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

PENGEMBANGAN MEDIA RUBIK CARD TEMATIK SUBTEMA SUMBER ENERGI KELAS IV SEKOLAH DASAR

Elementary School, 2020
The purpose of this study was to determine student responses after using the learning media developed, namely the Thematic Rubik Card. The trial was carried out on class IVB Khodijah and IVC Abdurrahman students at SDIT Permata Bunda Mranggen Demak.
Lusianti Eka Kurnia, Henry Januar Saputra, Khusnul Fajriyah   +2 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

KEEFEKTIFAN MODEL MAKE A MATCH TERHADAP MOTIVASI BELAJAR SISWA PADA PELAJARAN IPA TEMA 5 KELAS V SDN JATINGALEH 01 SEMARANG

Elementary School, 2019
Abstrak Penelitian ini bertujuan untuk mengetahui keefektifan model pembelajaran Make A Match terhadap motivasi belajar siswa pada pelajaran IPA tema 5 kelas V SDN Jatingaleh 01 Semarang.
Amalia Ayu Lestari, Muhajir, Henry Januar Saputra
doaj   +1 more source

PENERAPAN PENDEKATAN CONTEXTUAL TEACHING AND LEARNING (CTL) BERBASIS PERMAINAN UNTUK MENINGKATKAN MOTIVASI DAN PRESTASI BELAJAR PKn MATERI PENGARUH GLOBALISASI PADA SISWA KELAS IV SD 6 PUYOH

Elementary School, 2020
This study aims to increase the motivation and achievement of students in grade I V SD 6 Puyoh in the second semester of the 2017/2018 academic year in Civics by applying the contextual teaching and learning (CTL) approach based on game methods.To ...
Ashfiyah Ashfiyah
doaj   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

KEEFEKTIFAN MODEL PEMBELAJARAN CONCEPT SENTENCE TERHADAP KEMAMPUAN MENULIS PARAGRAF KELAS III SD NEGERI KARANGREJO 01 BONANG DEMAK

Elementary School, 2019
Abstrak Tujuan dalam penelitian ini adalah untuk mengetahui keefektifan model concept sentence terhadap kemampuan menulis paragraf siswa kelas III SD Negeri Karangrejo 01 Bonang Demak.
Anis Iqomatul Khaq, Muhajir
doaj   +1 more source

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte, Lucy Norcliffe‐Kaufmann, Maria Luisa Cotrina, Zenith Khan, Kaia Dalamo, Patricio Millar Vernetti, Matthew Lawless, Elisabetta Morini, Monica Salani, Marla Weetall, Jana Narasimhan, Agostino G. Rocha, Susan A. Slaugenhaupt, Horacio Kaufmann   +13 more
wiley   +1 more source