Results 101 to 110 of about 4,915,083 (312)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Trace Elements in Nutrition of Children

open access: yes, 1985
v.306 hal.; 22 ...
Trace Elements
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Unmasking Medical Frauds: Exposing the Details and Implications of Illicit Trade in the Medical Sector

open access: yes, 2022
This paper investigates how the evolution of the e-commerce market in conjunction with the extensive reach of globalization has brought about new ways for illicit trade to circumvent regulation, especially in the multibillion dollar industry that is the ...
Narayan, Nina, Elements
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Quelques elements structurels et economiques de l'agriculture belge.

open access: yes
Quelques elements structurels et economiques de l'agriculture ...
Elements
core  

The Demon of the Belfry: Investigating the Evolution of the Penny Press and the Emmanuel Church Murders

open access: yes, 2022
The Penny Press' sensational coverage of the 1895 Emmanuel Church Murders (committed by San Francisco Medical zstudent Theofore Durrant) highlighted their obsession with deviant sexuality and gruesome violence.
Stebbins, Sean, Elements
core  

Enabling Humans and AI Systems to Retrieve Information from System Architectures in Model-Based Systems Engineering

open access: yesSystems
The complexity of modern cyber–physical systems is steadily increasing as their functional scope expands and as regulations become more demanding.
Vincent Quast   +3 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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