Results 31 to 40 of about 2,519 (183)

Dual RNAseq analyses at soma and germline levels reveal evolutionary innovations in the elephantiasis-agent Brugia malayi, and adaptation of its Wolbachia endosymbionts.

PLoS Neglected Tropical Diseases, 2021
Brugia malayi is a human filarial nematode responsible for elephantiasis, a debilitating condition that is part of a broader spectrum of diseases called filariasis, including lymphatic filariasis and river blindness.
Germain Chevignon, Vincent Foray, Mercedes Maria Pérez-Jiménez, Silvia Libro, Matthew Chung, Jeremy M Foster, Frédéric Landmann   +6 more
doaj   +1 more source

Treatment of elephantiasis nostras verrucosa with CO2laser

Indian Dermatology Online Journal, 2019
Elephantiasis nostras verrucosa (ENV) is the most severe form of chronic non-filarial lymphedema that leads to disfiguration of body parts. Multiple topical and surgical treatments have been typically used with high relapse rates and local complications.
Adrián De Quintana Sancho, Leandra Reguero Del Cura, Susana Armesto Alonso, Marcos Antonio González López   +3 more
doaj   +1 more source

A Rare Cause of Massive Scrotal Elephantiasis: Case Report and Literature Review

Trends in Urology &Men's Health, Volume 16, Issue 6, December 2025.
ABSTRACT Scrotal lymphedema is a rare late complication of testicular cancer treatment, with most reported cases occurring in the early postoperative period. Massive scrotal elephantiasis manifesting more than a decade after postchemotherapy retroperitoneal lymph node dissection (pc‐RPLND) has not previously been described.
David Toro Tole, Jonathon Bowden, Bilal Mir, Joe Hedger, Sheshang Kamath   +4 more
wiley   +1 more source

Podoconiosis – non‐filarial geochemical elephantiasis – a neglected tropical disease? [PDF]

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2009
SummaryPodoconiosis or mossy foot is a form of non‐filarial lymphedema. This geo‐chemical elephantiasis is a disabling condition caused by the passage of microparticles of silica and aluminum silicates through the skin of people walking barefoot in areas with a high content of soil of volcanic origin.
Pietro, Nenoff, Jan Christoph, Simon, Grace K, Muylowa, Gail, Davey   +3 more
openaire   +2 more sources

Targeting Mitogen‐Activated Protein Kinase‐Activating Death Domain Protein of Brugia malayi for Construction of a Multi‐Epitope Subunit Vaccine Against Lymphatic Filariasis

Medicine Advances, Volume 3, Issue 3, Page 177-192, September 2025.
We focused on the MAP kinase activating death domain (MADD) protein of Brugia malayi as a candidate for a vaccine against lymphatic filariasis (LF). Our results demonstrated a significant increase in the production of memory B‐cells, T‐cells, and antibodies, which are crucial for removing microfilariae from the circulation of infected individuals. This
Paa Kwesi Anfu, Gifty Madjitey, Jennifer Afreh, Arnold Abakah, Prince Dunyo, Prince Manu, Kweku Foh Gyasi, Priscilla Osei‐Poku, Alexander Kwarteng   +8 more
wiley   +1 more source

Master of Puppets: How Microbiota Drive the Nematoda Ecology and Evolution?

Ecology and Evolution, Volume 15, Issue 8, August 2025.
The nematode microbiota can influence life‐history traits, thereby shaping the species' ecology and evolutionary trajectories. ABSTRACT In recent decades, the microbiota has emerged as a key driver of biological functions in metazoans, and nematodes are no exception.
Víctor José Trejo‐Meléndez, Jorge Contreras‐Garduño   +1 more
wiley   +1 more source

Unusual Benefit of Lumbar Sympathetic Block in Filarial Lymphedema

Indian Journal of Pain
Lymphatic filariasis, commonly known as elephantiasis, is a neglected tropical disease which causes hidden damage to the lymphatic system resulting in disfigurement, suffering, and poor quality of life.
Kritika Doshi
doaj   +1 more source

Epidemiology of elephantiasis with special emphasis on podoconiosis in Ethiopia: A literature review

Journal of Vector Borne Diseases, 2015
Elephantiasis is a symptom of a variety of diseases that is characterized by the thickening of the skin and underlying tissues, especially in the legs, male genitals and female breasts.
Mulat Yimer, Tadesse Hailu, Wondemagegn Mulu, Bayeh Abera   +3 more
doaj  

The Impact of Memory Effects on Lymphatic Filariasis Transmission Using Incidence Data From Ghana

Engineering Reports, Volume 7, Issue 7, July 2025.
Modeling Lymphatic Filariasis by incorporating disease awareness through fractional derivative operators. ABSTRACT Lymphatic filariasis is a neglected tropical disease caused by a parasitic worm transmitted to humans by a mosquito bite. In this study, a mathematical model is developed using the Caputo fractional operator.
Fredrick A. Wireko, Rebecca Awerigiya, Isaac K. Adu, Joshua N. Martey, Bernard O. Bainson, Joshua Kiddy K. Asamoah   +5 more
wiley   +1 more source

Neglected Tropical Diseases and Female Infertility: Possible Pathophysiological Mechanisms

Journal of Tropical Medicine, Volume 2025, Issue 1, 2025.
Battling female infertility has posed a global challenge, where neglected tropical diseases (NTDs) are nonetheless a notable contributing factor. NTDs affect a variety of diseases, often of a chronic nature, which are often cited as some of the most lethal diseases operating against the most economically disadvantaged populations across the globe.
Moses Agbomhere Hamed, Olabanji Ahmed Surakat, Victor Olukayode Ekundina, Kabirat Bolajoko Jimoh, Adetomiwa Ezekiel Adeogun, Nafisat Omolola Akanji, Oluwafemi Joshua Babalola, Patrick Chukwunonso Eya, Rajib Chowdhury   +8 more
wiley   +1 more source