Results 41 to 50 of about 2,519 (183)

Elephantiasis and verrucous lesions in an Ethiopian man living in Italy

Journal of Infection and Public Health
Elephantiasis refers to chronic, severe lymphedema caused by the abnormal accumulation of interstitial fluid due to reduced lymph transport and lymph stasis.
Benedetta Rossi, Federica Gottardi, Diego Segala, Claudia Zambelli, Stefano Iannazzi, Alberto Matteelli   +5 more
doaj   +1 more source

A Global Systematic Review on the Potential of Metal‐Based Nanoparticles in the Fight Against Mosquito Vectors

Journal of Tropical Medicine, Volume 2025, Issue 1, 2025.
Background: Mosquito‐borne diseases, such as malaria, filariasis, dengue, chikungunya, Zika, and other viral infections, pose significant public health challenges worldwide. For many years, chemical insecticides were used in the form of indoor residual spraying (IRS) and insecticide‐treated nets (ITNs).
Awoke Minwuyelet, Delenasaw Yewhalaw, Yibeltal Aschale, Andrea Sciarretta, Getnet Atenafu, Priya Gusain   +5 more
wiley   +1 more source

2022 German Society for Immunology Prizes

, 2022
European Journal of Immunology, Volume 52, Issue 10, Page 1541-1546, October 2022.
wiley   +1 more source

Prevalence of endemic Bancroftian filariasis in the high altitude region of south-eastern Nigeria [PDF]

Journal of Vector Borne Diseases, 2011
Background & objectives: The study was aimed at determining the prevalence and intensity of Wuchereriabancrofti microfilaraemia in a high altitude region of south-eastern Nigeria, and ascertaining the prevalenceof clinical signs and symptoms associated ...
E.C. Utta
doaj  

Anti-filarial immunity blocks parasite development and plays a protective role. [PDF]

PLoS ONE, 2018
Lymphatic filariasis is a complex parasitic disease having a spectrum of clinical parameters which are critical in deciding the severity of the pathogenesis. Individuals residing in the endemic areas are categorized into different clinical groups such as:
Prakash Kumar Sahoo, Santosh K Panda, Ashok Kumar Satapathy, Sanghamitra Pati   +3 more
doaj   +1 more source

Genetic, Immunological, and Public Health Perspectives on Podoconiosis

Journal of Tropical Medicine, Volume 2025, Issue 1, 2025.
Podoconiosis is a neglected tropical disease (NTD) that primarily affects poor communities in tropical regions, particularly in sub‐Saharan African countries. The disease results from prolonged contact with red clay soils, leading to chronic lymphedema of the lower limbs.
Tsegahun Asfaw Abebe, Abiola Isawumi, Lipi Buch   +2 more
wiley   +1 more source

Western Anthelmintics in Early Twentieth‐Century China Colonial Practices and Knowledge on “Tropical Diseases” of the In/between**

Berichte zur Wissenschaftsgeschichte, Volume 47, Issue 4, Page 330-351, December 2024.
Abstract Protestant (medical) missionaries were the main proponents of Western medicine in China after the Opium Wars. Several studies have highlighted how they used spectacular surgery as a means of gaining public trust. As well as surgery, they also administered anthelmintic drugs such as santonin as a tool of persuasion and conversion.
Dominik Merdes
wiley   +1 more source

Filarial parasites develop faster and reproduce earlier in response to host immune effectors that determine filarial life expectancy.

PLoS Biology, 2010
Humans and other mammals mount vigorous immune assaults against helminth parasites, yet there are intriguing reports that the immune response can enhance rather than impair parasite development.
Simon A Babayan, Andrew F Read, Rachel A Lawrence, Odile Bain, Judith E Allen   +4 more
doaj   +1 more source

Insulin receptor knockdown blocks filarial parasite development and alters egg production in the southern house mosquito, Culex quinquefasciatus. [PDF]

PLoS Neglected Tropical Diseases, 2018
Lymphatic filariasis, commonly known as elephantiasis, is a painful and profoundly disfiguring disease. Wuchreria bancrofti (Wb) is responsible for >90% of infections and the remainder are caused by Brugia spp.
Andrew Bradley Nuss, Mark R Brown, Upadhyayula Suryanarayana Murty, Monika Gulia-Nuss   +3 more
doaj   +1 more source

A Phase 1, Randomized, Double‐Blind, Placebo‐Controlled, Single Ascending Dose Trial of AWZ1066S, an Anti‐Wolbachia Candidate Macrofilaricide

Clinical Pharmacology in Drug Development, Volume 13, Issue 9, Page 1071-1081, September 2024.
Abstract AWZ1066S has been developed as a potential treatment for the neglected tropical diseases lymphatic filariasis and onchocerciasis. AWZ1066S targets the Wolbachia bacterial endosymbiont present in the causative nematode parasites. This phase 1, first‐in‐human study aimed to assess the safety and pharmacokinetics of AWZ1066S in healthy human ...
Graham Devereux, Marcin Bula, Karen Tripp, Richard Fitzgerald, Nicola Eraut, Muhammad Salman Alam, Tomoyuki Moriyama, Raku Shinkyo, Lauren Walker, Duolao Wang, Fabian Gusovsky, Jeannette van der Velde, Joseph D. Turner, Weiqian David Hong, Paul M. O'Neill, Mark J. Taylor, Stephen A. Ward   +16 more
wiley   +1 more source