Results 41 to 50 of about 4,044 (214)

The Potentials of Calotropis procera against Filarial Elephantiasis: An in- silico approach [PDF]

Journal of Parasitic Diseases, 2021
Abstract Lymphatic filariasis is one of the major diseases that belong to the category of neglected tropical illness. Filarial nematodes are the cause of the disease and are transmitted to humans via blood-feeding arthropod vectors. Drugs such as Albendazole, Ivermectin and diethylcarbamazine are administered either individually or in ...
Aswin Mohan, Shanitha Shaji, Sunitha Padmanabhan, Shahanas Naisam, Nidhin Sreekumar   +4 more
openaire   +2 more sources

Wuchereria bancrofti infection at four primary schools and surrounding communities with no previous blood surveys in northern Uganda: the prevalence after mass drug administrations and a report on suspected non-filarial endemic elephantiasis

Tropical Medicine and Health, 2017
Background A prevalence study of Wuchereria bancrofti infection was carried out in 2014 at 4 study sites in northern Uganda using antigen and microfilaria tests. Each study site consists of a primary school and surrounding communities.
Emmanuel Igwaro Odongo-Aginya, Alex Olia, Kilama Justin Luwa, Eiji Nagayasu, Anna Mary Auma, Geoffrey Egitat, Gerald Mwesigwa, Yoshitaka Ogino, Eisaku Kimura, Toshihiro Horii   +9 more
doaj   +1 more source

Most of the response elicited against Wolbachia surface protein in filarial nematode infection is due to the infective larval stage [PDF]

, 2004
Immune responses to the intracellular Wolbachia bacteria of filarial nematodes are thought to contribute to the pathologic process of filarial infection.
Allen, Judith E, Blaxter, Mark L, Fenn, Katelyn, Guiliano, David B, Kurniawan, Agnes, Lamb, Tracey J, Le Goff, Laetitia, Read, Andrew F   +7 more
core   +1 more source

Neglected tropical diseases, neglected data sources, and neglected issues. [PDF]

PLoS Neglected Tropical Diseases, 2007
BACKGROUND: Lymphatic filariasis (LF) is a so-called neglected tropical disease, currently overshadowed by higher-profile efforts to address malaria, tuberculosis, and HIV/AIDS.
Burton H Singer, Carol D Ryff
doaj   +1 more source

Pharmacokinetics, safety, and efficacy of a single co-administered dose of diethylcarbamazine, albendazole and ivermectin in adults with and without Wuchereria bancrofti infection in Cote d\u27Ivoire [PDF]

, 2019
BackgroundA single co-administered dose of ivermectin (IVM) plus diethylcarbamazine (DEC) plus albendazole (ALB), or triple-drug therapy, was recently found to be more effective for clearing microfilariae (Mf) than standard DEC plus ALB currently used ...
Bjerum, Catherine M, Chhonker, Yashpal S, Edi, Constant, King, Christopher L, Koudou, Benjamin G, Meite, Aboulaye, Murry, Daryl J, Ouattara, Allassane F, Penali, Louis K, Weil, Gary J   +9 more
core   +4 more sources

Podoconiosis – non‐filarial geochemical elephantiasis – a neglected tropical disease? [PDF]

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2009
SummaryPodoconiosis or mossy foot is a form of non‐filarial lymphedema. This geo‐chemical elephantiasis is a disabling condition caused by the passage of microparticles of silica and aluminum silicates through the skin of people walking barefoot in areas with a high content of soil of volcanic origin.
Pietro, Nenoff, Jan Christoph, Simon, Grace K, Muylowa, Gail, Davey   +3 more
openaire   +2 more sources

Neglected patients with a neglected disease? A qualitative study of lymphatic filariasis. [PDF]

PLoS Neglected Tropical Diseases, 2007
BACKGROUND: Lymphatic filariasis (LF) is a so-called neglected tropical disease, currently overshadowed by higher-profile efforts to address malaria, tuberculosis, and HIV/AIDS.
Myrtle Perera, Margaret Whitehead, David Molyneux, Mirani Weerasooriya, Godfrey Gunatilleke   +4 more
doaj   +1 more source

Wuchereria bancrofti: Unusual Presentation as Pancytopenia [PDF]

Journal of Clinical and Diagnostic Research, 2016
Wuchereria bancrofti is an endemic filarial nematode spread by a mosquito vector. The clinical manifestations vary from asymptomatic microfilaremeia to lymhoedema.
Mili Jain, Ayush Shukla, Ashutosh Kumar, Rashmi Kushwaha, Uma Shankar Singh   +4 more
doaj   +1 more source

Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden. [PDF]

, 2015
Parasitic helminth infections can be associated with lifelong morbidity such as immune-mediated organ failure. A better understanding of the host immune response to helminths could provide new avenues to promote parasite clearance and/or alleviate ...
A Tarkowski, AL Moncayo, AM Gan, B Min, Cathy Steel, CH Kuo, CM Steppan, D Artis, D Voehringer, DD Taub, DR Herbert, DR Herbert, DR Neill, Edward J. Pearce, F Chen, Gang Chen, GD Thomas, Graham Le Gros, H Helmby, HK Park, HS Jung, J Bethony, J Urban, J Wang, JA Jackson, Jessica C. Jang, JF Urban Jr, JI Odegaard, JJ Reece, Josiah I. Chung, JT Pesce, K Migita, KT Cuenco, L Boring, L Le Goff, L Patel, LC Osborne, M Lehrke, M Lehrke, M Qatanani, Mali Camberis, Mark A. Barnes, Meera G. Nair, MG Nair, MG Nair, MG Nair, Mitchell A. Lazar, MM Pirvulescu, MP Reilly, N Silswal, P Loke, PF Weller, Philip J. Cooper, PJ George, PJ Hotez, R Anuradha, RM Anthony, RT Semnani, RZ Yang, S Babu, S Babu, S Babu, S Babu, S Jiang, S Lee, Spencer H. Wang, Thomas B. Nutman, TT MacDonald, W He, Y Benomar, YY Hsieh   +70 more
core   +5 more sources

Dual RNAseq analyses at soma and germline levels reveal evolutionary innovations in the elephantiasis-agent Brugia malayi, and adaptation of its Wolbachia endosymbionts.

PLoS Neglected Tropical Diseases, 2021
Brugia malayi is a human filarial nematode responsible for elephantiasis, a debilitating condition that is part of a broader spectrum of diseases called filariasis, including lymphatic filariasis and river blindness.
Germain Chevignon, Vincent Foray, Mercedes Maria Pérez-Jiménez, Silvia Libro, Matthew Chung, Jeremy M Foster, Frédéric Landmann   +6 more
doaj   +1 more source