Results 61 to 70 of about 15,382 (175)

Targeting Mitogen‐Activated Protein Kinase‐Activating Death Domain Protein of Brugia malayi for Construction of a Multi‐Epitope Subunit Vaccine Against Lymphatic Filariasis

Medicine Advances, Volume 3, Issue 3, Page 177-192, September 2025.
We focused on the MAP kinase activating death domain (MADD) protein of Brugia malayi as a candidate for a vaccine against lymphatic filariasis (LF). Our results demonstrated a significant increase in the production of memory B‐cells, T‐cells, and antibodies, which are crucial for removing microfilariae from the circulation of infected individuals. This
Paa Kwesi Anfu, Gifty Madjitey, Jennifer Afreh, Arnold Abakah, Prince Dunyo, Prince Manu, Kweku Foh Gyasi, Priscilla Osei‐Poku, Alexander Kwarteng   +8 more
wiley   +1 more source

A rare entity of non-filarial lymphedema

Journal of Clinical Images and Medical Case Reports, 2021
Patient is a 77 year old female who presented to the outpatient dermatology clinic due to progressive massive leg swelling. Physical exam demonstrated bilateral lower extremity chronic lymphedema with stasis dermatitis changes with the left more ...
C. Stauch, M. Jafari, H. Polimera
semanticscholar   +1 more source

Master of Puppets: How Microbiota Drive the Nematoda Ecology and Evolution?

Ecology and Evolution, Volume 15, Issue 8, August 2025.
The nematode microbiota can influence life‐history traits, thereby shaping the species' ecology and evolutionary trajectories. ABSTRACT In recent decades, the microbiota has emerged as a key driver of biological functions in metazoans, and nematodes are no exception.
Víctor José Trejo‐Meléndez, Jorge Contreras‐Garduño   +1 more
wiley   +1 more source

Anti-filarial immunity blocks parasite development and plays a protective role. [PDF]

PLoS ONE, 2018
Lymphatic filariasis is a complex parasitic disease having a spectrum of clinical parameters which are critical in deciding the severity of the pathogenesis. Individuals residing in the endemic areas are categorized into different clinical groups such as:
Prakash Kumar Sahoo, Santosh K Panda, Ashok Kumar Satapathy, Sanghamitra Pati   +3 more
doaj   +1 more source

Macrophage-derived human resistin is induced in multiple helminth infections and promotes inflammatory monocytes and increased parasite burden. [PDF]

, 2015
Parasitic helminth infections can be associated with lifelong morbidity such as immune-mediated organ failure. A better understanding of the host immune response to helminths could provide new avenues to promote parasite clearance and/or alleviate ...
A Tarkowski, AL Moncayo, AM Gan, B Min, Cathy Steel, CH Kuo, CM Steppan, D Artis, D Voehringer, DD Taub, DR Herbert, DR Herbert, DR Neill, Edward J. Pearce, F Chen, Gang Chen, GD Thomas, Graham Le Gros, H Helmby, HK Park, HS Jung, J Bethony, J Urban, J Wang, JA Jackson, Jessica C. Jang, JF Urban Jr, JI Odegaard, JJ Reece, Josiah I. Chung, JT Pesce, K Migita, KT Cuenco, L Boring, L Le Goff, L Patel, LC Osborne, M Lehrke, M Lehrke, M Qatanani, Mali Camberis, Mark A. Barnes, Meera G. Nair, MG Nair, MG Nair, MG Nair, Mitchell A. Lazar, MM Pirvulescu, MP Reilly, N Silswal, P Loke, PF Weller, Philip J. Cooper, PJ George, PJ Hotez, R Anuradha, RM Anthony, RT Semnani, RZ Yang, S Babu, S Babu, S Babu, S Babu, S Jiang, S Lee, Spencer H. Wang, Thomas B. Nutman, TT MacDonald, W He, Y Benomar, YY Hsieh   +70 more
core   +5 more sources

The Impact of Memory Effects on Lymphatic Filariasis Transmission Using Incidence Data From Ghana

Engineering Reports, Volume 7, Issue 7, July 2025.
Modeling Lymphatic Filariasis by incorporating disease awareness through fractional derivative operators. ABSTRACT Lymphatic filariasis is a neglected tropical disease caused by a parasitic worm transmitted to humans by a mosquito bite. In this study, a mathematical model is developed using the Caputo fractional operator.
Fredrick A. Wireko, Rebecca Awerigiya, Isaac K. Adu, Joshua N. Martey, Bernard O. Bainson, Joshua Kiddy K. Asamoah   +5 more
wiley   +1 more source

Neglected Tropical Diseases and Female Infertility: Possible Pathophysiological Mechanisms

Journal of Tropical Medicine, Volume 2025, Issue 1, 2025.
Battling female infertility has posed a global challenge, where neglected tropical diseases (NTDs) are nonetheless a notable contributing factor. NTDs affect a variety of diseases, often of a chronic nature, which are often cited as some of the most lethal diseases operating against the most economically disadvantaged populations across the globe.
Moses Agbomhere Hamed, Olabanji Ahmed Surakat, Victor Olukayode Ekundina, Kabirat Bolajoko Jimoh, Adetomiwa Ezekiel Adeogun, Nafisat Omolola Akanji, Oluwafemi Joshua Babalola, Patrick Chukwunonso Eya, Rajib Chowdhury   +8 more
wiley   +1 more source

2022 German Society for Immunology Prizes

, 2022
European Journal of Immunology, Volume 52, Issue 10, Page 1541-1546, October 2022.
wiley   +1 more source

Epidemiology of elephantiasis with special emphasis on podoconiosis in Ethiopia: A literature review

Journal of Vector Borne Diseases, 2015
Elephantiasis is a symptom of a variety of diseases that is characterized by the thickening of the skin and underlying tissues, especially in the legs, male genitals and female breasts.
Mulat Yimer, Tadesse Hailu, Wondemagegn Mulu, Bayeh Abera   +3 more
doaj  

Insulin receptor knockdown blocks filarial parasite development and alters egg production in the southern house mosquito, Culex quinquefasciatus. [PDF]

PLoS Neglected Tropical Diseases, 2018
Lymphatic filariasis, commonly known as elephantiasis, is a painful and profoundly disfiguring disease. Wuchreria bancrofti (Wb) is responsible for >90% of infections and the remainder are caused by Brugia spp.
Andrew Bradley Nuss, Mark R Brown, Upadhyayula Suryanarayana Murty, Monika Gulia-Nuss   +3 more
doaj   +1 more source