Results 91 to 100 of about 716,525 (313)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Responses of ectomycorrhizal fungi to changes in carbon and nutrient availability [PDF]

open access: yes, 2001
Ectomycorrhizal (ECM) fungi may receive 20% of the total C fixed by their host plants and are essential components of host nutrient acquisition. As a consequence of the vast physiological diversity that exists among ECM fungi, changes in community ...
Fransson, Petra M.A.
core  

Elevated CO2 and Warming Altered Grassland Microbial Communities in Soil Top-Layers. [PDF]

open access: yes, 2018
As two central issues of global climate change, the continuous increase of both atmospheric CO2 concentrations and global temperature has profound effects on various terrestrial ecosystems.
Deng, Ye   +10 more
core   +4 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Plant adaptation or acclimation to rising CO2? Insight from first multigenerational RNA-Seq transcriptome

open access: yes, 2016
Atmospheric carbon dioxide (CO2) directly determines the rate of plant photosynthesis and indirectly effects plant productivity and fitness and may therefore act as a selective pressure driving evolution, but evidence to support this contention is sparse.
Ainsworth   +57 more
core   +1 more source

Top-down control by Harmonia axyridis mitigates the impact of elevated atmospheric CO2 on a plant-aphid interaction [PDF]

open access: yes, 2014
1. The present study investigated the impact of elevated atmospheric CO2 (390 or 650 μmol/mol) on raspberry genotypes varying in resistance to the large raspberry aphid Amphorophora idaei and any subsequent impact on the coccinellid predator Harmonia ...
Hails, Rosemary S.   +4 more
core   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Growth and Quality Responses of Potato to Elevated [CO2]

open access: yes, 2006
Root and tuber crops are highly important food resources. They comprise several genera and supply the main part of the daily carbohydrate intake of large populations. These carbohydrates are mostly starches found in storage organs, which may be enlarged roots, corms, rhizomes, or tubers.
M Bindi   +4 more
openaire   +2 more sources

Growth in elevated CO2 enhances temperature response of photosynthesis in wheat [PDF]

open access: yes, 2008
The temperature dependence of C3 photosynthesis may be altered by the growth environment. The effects of long-term growth in elevated CO2 on photosynthesis temperature response have been investigated in wheat (Triticum aestivum L.) grown in controlled
Alonso, Aitor   +2 more
core   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

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