Results 71 to 80 of about 716,525 (313)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Physiological and molecular basis of promoting leaf growth in strawberry (Fragaria ananassa Duch.) by CO2 enrichment

open access: yesBiotechnology & Biotechnological Equipment, 2020
Strawberry (Fragaria ananassa Duch.) is an economically important crop. Its yield is highly dependent on photosynthesis, and carbon dioxide (CO2) is one of the most important constituents in photosynthesis.
Xuan Li   +9 more
doaj   +1 more source

Short-Term Uptake of 15N by a Grass and Soil Micro-Organisms after Long-Term Exposure to Elevated CO2 [PDF]

open access: yes, 2018
This study examines the effect of elevated CO2 on short-term partitioning of inorganic N between a grass and soil micro-organisms. 15N-labelled NH4+ was injected in the soil of mesocosms of Holcus lanatus (L.) that had been grown for more than 15months ...
Barnard, Romain   +2 more
core  

Nutrient relations in calcareous grassland under elevated CO2 [PDF]

open access: yes, 1998
Plant nutrient responses to 4 years of CO2 enrichment were investigated in situ in calcareous grassland. Beginning in year 2, plant aboveground C:N ratios were increased by 9% to 22% at elevated CO2 (P > 0.01), depending on year.
Körner, Christian   +3 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Evaluation of the Effect of Photosynthesis on Biomass Production with Simultaneous Analysis of Growth and Continuous Monitoring of CO2 Exchange in the Whole Plants of Radish, cv Kosena under Ambient and Elevated CO2

open access: yesPlant Production Science, 2004
The effects of elevated CO2 (approximate doubling of atmospheric CO2 concentration) on the rate of photosynthesis estimated from continuous monitoring of CO2 exchange in whole plants were investigated in radish cv.
Hideaki Usuda
doaj   +1 more source

Atmospheric CO2 Concentration and N Availability Affect the Balance of the Two Photosystems in Mature Leaves of Rice Plants Grown at a Free-Air CO2 Enrichment Site

open access: yesFrontiers in Plant Science, 2020
Atmospheric CO2 concentration ([CO2]) has been substantially increasing. Responses of leaf photosynthesis to elevated [CO2] have been intensively investigated because leaf photosynthesis is one of the most important determinants of crop yield.
Hiroshi Ozaki   +5 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Elevated carbon dioxide enhances the growth and reduces the antifungal susceptibility of Histoplasma capsulatum

open access: yesMicrobiology Spectrum
Histoplasma capsulatum is a thermally dimorphic fungal pathogen. It causes approximately 500,000 infections annually in the United States. Histoplasma is present as avirulent mycelia in the soil and transforms into pathogenic yeasts at the human body ...
Qian Shen, Kelsey Steinmetz
doaj   +1 more source

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