Results 71 to 80 of about 212,868 (349)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Research on the Aerodynamic Characteristics of an Ultrahigh-speed Elevator During the Staggering Process Between the Car and Counterweight [PDF]

open access: yesJournal of Applied Fluid Mechanics
Investigating the aerodynamic characteristics of an ultrahigh-speed elevator between the car and counterweight during the staggering process is crucial for the development of drag reduction and noise abatement technologies.
B. Liu   +7 more
doaj   +1 more source

Experimental and analytical transonic flutter characteristics of a geared-elevator configuration [PDF]

open access: yes
The flutter model represented the aft fuselage and empennage of a proposed supersonic transport airplane and had an all movable horizontal tail with a geared elevator. It was tested mounted from a sting in the transonic dynamics tunnel. Symmetric flutter
Doggett, R. V., Jr.   +2 more
core   +1 more source

Development and Wind Tunnel Evaluation of a SMA Based Trim Tab Actuator for a Civil Aircraft [PDF]

open access: yes, 2011
This paper presents about the development and wind tunnel evaluation of an SMA based smart trim tab for a typical 2 seater civil aircraft. SMA actuator was housed in the port side of the elevator for actuating the trim tab.
Dayananda, GN   +5 more
core  

Feedback methods for inverse simulation of dynamic models for engineering systems applications [PDF]

open access: yes, 2011
Inverse simulation is a form of inverse modelling in which computer simulation methods are used to find the time histories of input variables that, for a given model, match a set of required output responses.
Anonymous   +20 more
core   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Diagnostic Tools For The Elevator Business [PDF]

open access: yes, 2010
Although much has been written about elevator maintenance from the engineering perspective, little has been written about elevator maintenance from a business perspective.
Ehoff, Clemense, Jr.
core   +3 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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