Results 101 to 110 of about 121,386 (258)

Mechanoadaptation via Myosin Cytoplasmic Redistribution Protects Circulating Tumor Cells From Shear‐induced Death During Hematogenous Dissemination

Advanced Science, EarlyView.
This study investigates how CTCs survive varying shear stress during hematogenous metastasis. We uncover a self‐protection mechanism, by which non‐adherent CTCs adapt to high shearing milieu through accumulated cytoplasmic myosin‐mediated disruption of myosin‐actin binding, attenuating force transmission into chromatin to protect CTCs from shear ...
Cunyu Zhang, Qianchun Wang, Keming Li, Guanshuo Hu, Ying Xin, Kai Tang, Bing Hu, Pengyu Du, Renwei Mao, Baohua Ji, Youhua Tan   +10 more
wiley   +1 more source

Tuning Defects in Ni‐Doped Maghemite for Enhanced Solar Driven Oxygen Evolution: Insights From Operando X‐Ray Spectroscopies

Advanced Science, EarlyView.
ABSTRACT Maghemite (γ$\gamma$‐Fe2${\rm Fe}_2$O3${\rm O}_{3}$) is a promising non‐precious‐metal‐containing photocatalyst for water oxidation (OER). Despite being less studied than Hematite, it offers similar corrosion resistance and a favorable band structure, along with higher conductivity and the advantage of an adaptable spinel structure.
Francesco Paparoni, Hélène Magnan, Antoine Barbier, Andrea Zitolo, AndreaDi Cicco, Javad Rezvani, Emiliano Fonda   +6 more
wiley   +1 more source

Tumor‐Induced Splenic Remodeling: Mechanisms of Systemic Immunosuppression and Emerging Therapeutic Opportunities

Advanced Science, EarlyView.
ABSTRACT Despite the transformative impact of cancer immunotherapies such as immune checkpoint blockade, durable clinical responses remain limited. Increasing evidence indicates that antitumor immunity is governed not only by the tumor microenvironment, but also by systemic immune regulation mediated by peripheral immune organs. Among these, the spleen
Yuehua Liu, Xiaoqian Nie, Xiaofei Gao
wiley   +1 more source

Molecularly Bridged Heterointerface Engineering: Designing Transparent, Wear‐Resistant, Hard yet Flexible Optoelectronic Protective Film

Advanced Science, EarlyView.
A molecular‐bridging heterogeneous interface engineering strategy is introduced to combine a polyhedral oligomeric silsesquioxane (POSS)‐based hard coating with a colorless polyimide (CPI)‐based flexible layer. The robust heterogeneous interface endows the integrated system with the superior properties of both layers and their synergistic ...
Huiyang Lu, Zihui Liu, Jianan Yuan, Yunhao Wei, Shuangfei Xiang, Qinghua Lu   +5 more
wiley   +1 more source

Flexible Pressure Sensor With Multi‐Stage Microdome Structure Enabling Ultra‐Wide Linear Range and High Sensitivity for Wearable Applications

Advanced Science, EarlyView.
An MXene‐based flexible piezoresistive sensor featuring a multi‐stage microdome architecture is developed, which simultaneously realizes high sensitivity of 11.57 kPa−1 and an ultra‐broad detection range up to 2500 kPa. When integrated into palm and sole sensor arrays combined with deep learning algorithms, it achieves a recognition accuracy of over 95%
De‐Yu Kong, Kai Wang, Jia‐Nan Ma, Bo‐Ma, Teng‐Teng Gao, Hai‐Wang Zhang, Hong‐Tao Wang, Qiang Li, Hui Gao, Sheng‐Bo Sang   +9 more
wiley   +1 more source

Directed Evolution Improves the Catalytic Efficiency of APEX2‐Mediated Proximity‐Dependent RNA Labeling

Advanced Science, EarlyView.
ABSTRACT Engineered ascorbate peroxidase APEX2 has been widely used for spatially restricted profiling of subcellular biomolecules, but its catalytic efficiency toward newly developed probes such as biotin‐aniline (Btn‐An) remains suboptimal. To overcome this limitation, we performed yeast surface display‐based directed evolution to enhance APEX2 ...
Gang Wang, Yi Li, Peiyuan Meng, Peng Zou
wiley   +1 more source

Self‐Powered Bearing Sensing and Real‐Time Fault Diagnosis Enabled by Non‐Invasive Triboelectric Sensors and Edge AI Acceleration

Advanced Science, EarlyView.
This study achieves the synergistic integration of self‐powered sensing and edge AI acceleration to establish a real‐time fault diagnosis system. The proposed TENG‐based self‐powered bearing sensor (NSE‐TBS) and FPGA‐accelerated edge AI framework fundamentally break through the inherent limitations of conventional monitoring systems, including complex ...
Kehui Zhu, Zhongheng Liu, Xinming Li, Jinrui Zhang, Meng Li, Yiming Guo, Lihua Han, Yanxue Wang   +7 more
wiley   +1 more source

Online Wellhead Drill Pipe Inspection Method Based on Open⁃Loop Permanent Magnet Magnetization

Shiyou jixie
The service safety of drill pipes （DPs） during drilling is critical in deep and ultra⁃deep wells. The closed⁃loop U⁃type permanent magnet （PM） magnetization method， one of the existing wellhead DP magnetic flux leakage （MFL） inspection techniques ...
Ke Rui, Wu Jianbo, Deng Chengjun, Liu Zhaoting, Xia Hui, Luo Yang, Guan Qingbin   +6 more
doaj  

Data‐Driven Modeling of Composition–Processing–Microstructure Relations for Recycled Aluminum Cast Alloys

Advanced Science, EarlyView.
Interpretable machine learning reveals how composition and processing govern the formation and microstructural burden of Fe‐rich intermetallic compounds in recycled Al–Si–Fe–Mn alloys. By separating morphology selection from morphology‐conditioned burden partitioning, this framework shows that identical Fe contents can yield different intermetallic ...
Jaemin Wang, Waleed Mohammed, Dierk Raabe   +2 more
wiley   +1 more source

Quantum Dots for Biomedical Biosensing, NIR‐II Bioimaging, and Phototherapy: Materials Design, Signal Transduction, and Translational Barriers

Advanced Science, EarlyView.
This review outlines bottom‐up and biomimetic fabrication strategies of quantum dots, and highlights their emerging applications in biosensing, multimodal bioimaging, and intelligent cancer theranostics. It further discusses key translational barriers and future perspectives for advancing QD‐based nanomedicine toward clinical implementation.
Jie Ju, Zhifang Liu, Xinran Gao, Wen Sun, Wei Fu, Yanfei Wang   +5 more
wiley   +1 more source