Results 21 to 30 of about 788,268 (259)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

La convivencia en la escuela. entre el deber ser y la realidad

Revista Latinoamericana de Estudios Educativos, 2017
Este artículo es resultado de una investigación orientada con el propósito de develar las concepciones y los modelos de gestión de la convivencia escolar de directivos y docentes de instituciones educativas urbanas del sector público y privado de los ...
Paula Patricia Peña Figueroa, Jacqueline Sánchez Prada, Jacqueline Ramírez Sánchez   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

O PROGRAMA UM MILHÃO DE CISTERNAS (P1MC): UMA ALTERNATIVA DE CONVIVÊNCIA COM O SEMIÁRIDO NA COMUNIDADE AGRESTE DE BAIXO – SÃO MIGUEL/RN

Caminhos de Geografia, 2017
O Programa Um Milhão de Cisternas (P1MC), criado em 1999 pela Articulação do Semiárido Brasileiro (ASA), sendo incorporado pela agenda das políticas públicas no ano de 2003 emerge como uma das ações de fomento a convivência com o Semiárido brasileiro ...
Ronaldo Valentim de Carvalho, Francisca Elisonete de Souza Lima, Rafael Pereira da Silva   +2 more
doaj   +1 more source

Dispareunia and vaginism, sexual disorders due to pain

Revista Cubana de Medicina Militar, 2020
Introduction: Within sexual disorders due to pain, dyspareunia and vaginismus are studied. The Diagnostic and Statistical Manual of Mental Disorders V encompasses them under the category of pelvic pain and penetration disorder.
Lessing Spengler González, Elvia de Dios Blanco, Lourdes Roque Ortega, Dolores Maurisset Moraguez   +3 more
doaj   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Comparison of bovine pregnancy associated glycoproteins (bpag- serum and milk), bovine pregnancy specific protein b (bpsp-b) tests with each other and with transrectal ultrasonographic findings for early pregnancy diagnosis [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2018
The aim of this study was to compare the accuracy of bovine pregnancy-associated glycoproteins (bPAG) and bovine pregnancy-specific protein B (bPSP-B) tests with transrectal ultrasonography (TRUS) for early pregnancy diagnosis in dairy cows.
Osman ERGENE, Isfendiyar DARBAZ, Serkan SAYINER, Selim ASLAN   +3 more
doaj   +1 more source

Cylindera (Eugrapha) elisae subsp. elisae elisae (Motschulsky 1859

, 2019
Published as part of Fukuda, Yuki, Ogawa, Ryo & Hori, Michio, 2019, The reclassification of Sophiodela and other tiger beetles (Coleoptera, Cicindelidae) based on the structure of the everted internal sac of the male genitalia, pp.
Fukuda, Yuki, Ogawa, Ryo, Hori, Michio
openaire   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source