Results 31 to 40 of about 1,167,280 (298)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

O PROGRAMA UM MILHÃO DE CISTERNAS (P1MC): UMA ALTERNATIVA DE CONVIVÊNCIA COM O SEMIÁRIDO NA COMUNIDADE AGRESTE DE BAIXO – SÃO MIGUEL/RN

Caminhos de Geografia, 2017
O Programa Um Milhão de Cisternas (P1MC), criado em 1999 pela Articulação do Semiárido Brasileiro (ASA), sendo incorporado pela agenda das políticas públicas no ano de 2003 emerge como uma das ações de fomento a convivência com o Semiárido brasileiro ...
Ronaldo Valentim de Carvalho, Francisca Elisonete de Souza Lima, Rafael Pereira da Silva   +2 more
doaj   +1 more source

Differentiation of Foot-and-Mouth Disease-Infected pigs from Vaccinated Pigs Using Antibody-Detecting Sandwich ELISA

, 2011
The presence of serum antibodies for nonstructural proteins of the foot-and-mouth disease virus (FMDV) can differentiate FMDV-infected animals from vaccinated animals.
Ming-Hwa JONG, Dekker, A., Wen-Bin CHUNG, Lin, Y.L., Fan LEE, Yeou-Liang LIN, Chen, T.H., Ming-Chang LEE, Chu-Hsiang PAN, Hsiang-Jung TSAI, Aldo DEKKER, Lee, M.C., Tsai, H.J., Tsu-Han CHEN, Chin-Cheng HUANG, Chung, W.B., Pan, C.H., Jong, M.H., Huang, C.C., Lee, F.   +19 more
core   +1 more source

Cylindera (Eugrapha) elisae subsp. elisae elisae (Motschulsky 1859

, 2019
Published as part of Fukuda, Yuki, Ogawa, Ryo & Hori, Michio, 2019, The reclassification of Sophiodela and other tiger beetles (Coleoptera, Cicindelidae) based on the structure of the everted internal sac of the male genitalia, pp.
Fukuda, Yuki, Ogawa, Ryo, Hori, Michio
openaire   +2 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Cylindera (Eugrapha) elisae subsp. elisae elisae (Motschulsky 1859

, 2017
Published as part of Wiesner, Jürgen, Bandinelli, Aligi & Matalin, Andrey, 2017, Notes on the tiger beetles (Coleoptera: Carabidae: Cicindelinae) of Vietnam. 135. Contribution towards the knowledge of Cicindelinae, pp.
Wiesner, Jürgen, Bandinelli, Aligi, Matalin, Andrey   +2 more
openaire   +2 more sources

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Comparison of bovine pregnancy associated glycoproteins (bpag- serum and milk), bovine pregnancy specific protein b (bpsp-b) tests with each other and with transrectal ultrasonographic findings for early pregnancy diagnosis [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2018
The aim of this study was to compare the accuracy of bovine pregnancy-associated glycoproteins (bPAG) and bovine pregnancy-specific protein B (bPSP-B) tests with transrectal ultrasonography (TRUS) for early pregnancy diagnosis in dairy cows.
Osman ERGENE, Isfendiyar DARBAZ, Serkan SAYINER, Selim ASLAN   +3 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Dispareunia and vaginism, sexual disorders due to pain

Revista Cubana de Medicina Militar, 2020
Introduction: Within sexual disorders due to pain, dyspareunia and vaginismus are studied. The Diagnostic and Statistical Manual of Mental Disorders V encompasses them under the category of pelvic pain and penetration disorder.
Lessing Spengler González, Elvia de Dios Blanco, Lourdes Roque Ortega, Dolores Maurisset Moraguez   +3 more
doaj   +2 more sources