Results 41 to 50 of about 788,268 (259)
FEBS Open Bio, EarlyView.In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Il 1911 in Maremma: le celebrazioni del Cinquantenario e il dibattito sull’“unificazione mancata”
Diacronie. Studi di Storia Contemporanea, 2018 According to recent trends in the historiography of the Risorgimento, this contribution examines contents and features of the celebration of the 50th anniversary of Italy’s Unification in the Tuscan area known as Maremma grossetana.
Elisa TIZZONI ha conseguito il Dottorato di ricerca in Storia Contemporanea presso l’Università di Pisa ed è attualmente cultore della materia presso l’Università di Firenze; i suoi interessi di ricerca riguardano principalmente i tourism studies, analizzati da un punto di vista istituzionale e culturale, le questioni relative al rapporto città-campagna e le dinamiche del processo di integrazione europea.
doaj
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Emergenza e sviluppo dell’azione delle organizzazioni internazionali in Colombia (1949-1954)
Diacronie. Studi di Storia Contemporanea, 2010 Nel 1949 l’International Bank for Reconstruction and Development svolge una General Survey Mission in Colombia. Si tratta di uno dei primi interventi dell’organizzazione nonché della prima missione intesa ad analizzare il complesso delle condizioni ...
Elisa Grandi è dottoranda in Storia d’Europa/Storia e Civiltà Comparata presso l’Université Paris VII – Denis Diderot e, in cotutela, con l’Università di Bologna. Sta conducendo una ricerca dal titolo: Reti Sociali e cambiamenti istituzionali. International economic advising, amministrazione pubblica e riforme economiche in Colombia (1949-1970). Nell’ambito delle sue ricerche ha rivolto la sua attenzione alla metodologia della ricerca storica, in particolare all’applicazione di tecniche proprie della ricerca economica e della sociologia alle scienze storiche.
doaj
Revista de la Facultad de Medicina, 2019 Introducción. La prevalencia de la infección por el virus de inmunodeficiencia humana (VIH) en Latinoamérica no ha sido estudiada de forma adecuada, pero se calcula que en Chile la mitad de los pacientes que están infectados no han sido diagnosticados y ...
Gustavo Saint-Pierre-Contreras +2 more
doaj +1 more source
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
FEBS Open Bio, EarlyView.Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Clinical Validation of Plasma p‐217tau in Neurological Diseases
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi +13 more
wiley +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Optical Variability of HBLs on Diverse Timescales
GalaxiesSince their discovery almost 60 years ago, BL Lac objects have been defined by their strong optical variability and their classification in the spectral energy distribution scheme.
Ileana Andruchow +2 more
doaj +1 more source
The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp +4 more
wiley +1 more source