Results 51 to 60 of about 1,748,841 (287)
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Emergenza e sviluppo dell’azione delle organizzazioni internazionali in Colombia (1949-1954)
Diacronie. Studi di Storia Contemporanea, 2010 Nel 1949 l’International Bank for Reconstruction and Development svolge una General Survey Mission in Colombia. Si tratta di uno dei primi interventi dell’organizzazione nonché della prima missione intesa ad analizzare il complesso delle condizioni ...
Elisa Grandi è dottoranda in Storia d’Europa/Storia e Civiltà Comparata presso l’Université Paris VII – Denis Diderot e, in cotutela, con l’Università di Bologna. Sta conducendo una ricerca dal titolo: Reti Sociali e cambiamenti istituzionali. International economic advising, amministrazione pubblica e riforme economiche in Colombia (1949-1970). Nell’ambito delle sue ricerche ha rivolto la sua attenzione alla metodologia della ricerca storica, in particolare all’applicazione di tecniche proprie della ricerca economica e della sociologia alle scienze storiche.
doaj
Revista de la Facultad de Medicina, 2019 Introducción. La prevalencia de la infección por el virus de inmunodeficiencia humana (VIH) en Latinoamérica no ha sido estudiada de forma adecuada, pero se calcula que en Chile la mitad de los pacientes que están infectados no han sido diagnosticados y ...
Gustavo Saint-Pierre-Contreras +2 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Diacronie. Studi di Storia Contemporanea, 2011 International economic advising is built on the complex interaction between different actors on many levels. Multiple entities are positioned between international lending institutions and local governments in the coordination of development programs ...
Elisa GRANDI est doctorante en histoire contemporaine et histoire de l’Amérique Latine à l’Université Paris Diderot et membre du laboratoire SEDET. Sa thèse Réseaux Sociaux et changement institutionnel. Experts internationaux, médiation politique et reformes économiques en Colombie (1949-1966), sous la direction de Zacarias Moutoukias, porte sur les réseaux reliant les experts de la Banque Mondiale et le personnel local en Colombie lors des premières missions de la Banque dans le pays. Après avoir été Visiting Student à la Duke University et Visiting Scholar à la New School of Social Research, elle est actuellement boursière du Gouvernement français Eiffel-Excellence à l’Université Paris Diderot.
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Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Interactive Water Quality Data Visualization: Case Study Longhorn Stream Team [PDF]
, 2016 Water quality monitoring can provide a real-time indicator as to the health and quality of a precious natural resource yet it is difficult to effectively communicate data and inspire action beyond the scientific arena.
Friedmann, Elisa
core +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
(Re)pensando a citação em textos acadêmico-científicos
Signum: Estudos da Linguagem, 2011 Este trabalho tem como objetivo discutir sobre a citação no texto acadêmico-científico. Argumentamos em favor da necessidade de se reivindicar o citar em sua dimensão dialógica, partindo do pressuposto de que o olhar concebido pelos manuais de ...
José Cezinaldo Rocha Bessa
doaj +1 more source