Results 91 to 100 of about 2,703 (241)

Vacancy defect‐induced electron homing breaks phosphodiester bonds for RNA depletion‐driven cancer therapy

BMEMat, EarlyView.
Illustration of 5% S‐vacancy Bi2S3 mediated phosphodiester bonds cleavage in RNA of hepatocellular carcinoma cells, which suppressing ERI3 expression, inhibiting cell proliferation and promoting apoptosis. Abstract Genome‐wide hypertranscription is a hallmark of malignant progression.
Chuncheng Yang, Zehao Shen, Guangming Xiang, Zhe Liu, Huaxin Liu, Jiabei Li, Ao Wang, Yelin Wu, Peiran Zhao, Xingwu Jiang, Jinghan Wang, Xiaoqing Jiang, Wenbo Bu   +12 more
wiley   +1 more source

Adaptive Control of Freedom Upper-Limb Exoskeleton Robots Using Extreme Learning Machine and Terminal Sliding Mode

Majlesi Journal of Electrical Engineering
This paper presents a novel Adaptive Dynamic Terminal Sliding Mode Controller (ADTSMC) with an exponential reaching law, specifically designed for precise position control of 5-Degree of Freedom (DOF) upper-limb exoskeleton robots.
Morteza Mirzaee, Reza Kazemi
doaj   +1 more source

Dual‐targeted nanomedicine delivering doxorubicin and nitric oxide for tumor immunomodulation and synergistic therapy

BMEMat, EarlyView.
The mechanism of HA‐DS@PLGA nanoparticles co‐delivering DOX and SNAP (an NO donor) to suppress tumor growth, remodel the tumor microenvironment, and enhance antitumor immune responses for effective combinatorial cancer therapy. Abstract Cancer therapeutic efficacy is significantly influenced by tumor immunosuppressive environment possibly induced by ...
Xingzhou Peng, Wei Chen, Shuyu Li, Xiaomin Ma, Yanfeng Dai, Yan Wang, Changqiang Xie, Yazhe Xiao, Hesong Han, Yumiao Zhang, Junjie Wang   +10 more
wiley   +1 more source

Origin of the up/down poloidal asymmetric dependence of ELM control in ITER-like RMP configuration in KSTAR

Nuclear Fusion
Recent edge-localized modes (ELM) control experiments via resonant magnetic perturbation (RMP) in KSTAR have shown a strong up/down poloidal asymmetric coupling dependence.
Inhwan Choi, Yueqiang Liu, Yongkyoon In
doaj   +1 more source

Near‐infrared light‐activated aptamer‐based nanoprobe for spatiotemporally resolved detection of L‐lactate in colorectal cancer

BMEMat, EarlyView.
A near‐infrared (NIR) light‐activated “lock‐key” nanodevice is reported for spatiotemporally resolved detection of intratumoral L‐lactate. The system stays silent until deep‐penetrating NIR light remotely unlocks its function, allowing for precise sensing within tumors.
Siyu Pan, Xuanyi Lu, Wenjie Yang, Yunhui Peng, Lingfu Deng, Shuai Zha, Xueyang Fang, Guochen Bao, Lijun Jiang   +8 more
wiley   +1 more source

Investigation of divertor heat flux characteristics under the influence of resonant magnetic perturbations on EAST

Nuclear Fusion
Controlling the splitting divertor heat flux caused by resonant magnetic perturbations (RMPs) is a topic of concern for fusion devices. As a fundamental prerequisite, it is necessary to understand the characteristics of the heat flux distribution under ...
Ruirong Liang, Xianzu Gong, Bin Zhang, Manni Jia, Hua Yang, Qun Ma, Youwen Sun, Zhendong Yang, Yunchan Hu, Zuhao Wang, Wei Wang, Yutong Guo, Jinwen Song, Jinping Qian, the EAST Team   +14 more
doaj   +1 more source

Loss, persistence and reversal of phenotypic traits

Biological Reviews, EarlyView.
ABSTRACT The irreversibility of complex trait loss has long been a tenet of evolutionary biology. However, this idea is increasingly at odds with the numerous documented exceptions across the Tree of Life. We synthesise this growing body of evidence across a diverse array of taxa and traits, exploring the evolutionary conditions that enable ...
Giobbe Forni, Giuseppe Fusco, Filippo Nicolini, Heather Bruce, Andrea Luchetti   +4 more
wiley   +1 more source

From Confusion to Clarity: A Multi‐Stage Process Framework for Understanding Consumer Confusion

Journal of Consumer Behaviour, EarlyView.
ABSTRACT This paper reconceptualizes consumer confusion as a multi‐stage temporal process rather than a static outcome, addressing theoretical fragmentation in existing antecedent‐consequence models. By integrating cognitive appraisal, contextual amplification, and adaptive coping within a unified framework, we explain how confusion unfolds rather than
Fatih Celik, Erdogan Koc
wiley   +1 more source

Impact of toroidal magnetic field direction on integrated ELM-stable operation and divertor power exhaust via boron powder injection in EAST

Nuclear Fusion
We report the first in-depth comparison of the impact of toroidal magnetic field direction on solid boron injection used for Edge-Localized Mode (ELM) control, power exhaust, and core high- Z impurity control in the Experimental Advanced Superconducting ...
Zhen Sun, Rajesh Maingi, Lei Peng, Xin Lin, Wei Xu, Zhe Wang, Qingquan Yang, Genfan Ding, Fang Ding, Kaifu Gan, Ahmed Diallo, Kevin Tritz, Tianfu Zhou, Yifeng Wang, Liang Chen, Kaixuan Ye, Wei Wang, Yunxin Cheng, Lingyi Meng, Yifei Jin, Ling Zhang, Yanmin Duan, Jizhong Sun, Alexander Nagy, Alessandro Bortolon, Guizhong Zuo, Jinping Qian, Xianzu Gong, Jiansheng Hu, the EAST Team   +29 more
doaj   +1 more source

Eco‐Friendly Synthesis of Cobalt Phthalocyanine for High‐Efficiency CO2${\rm CO}_{2}$ Electroreduction

Chemistry – A European Journal, EarlyView.
A sustainable synthesis of cobalt phthalocyanine (CoPc) using low‐impact solvents yields high‐performance electrocatalysts with reduced waste (E‐factor 18.6). When integrated into gas diffusion electrodes, CoPc achieves up to 12% Faradays efficiency for CO2‐to‐methanol and 65% CO2‐to‐CO conversion, aligning with state‐of‐the‐art materials and enabling ...
Gloria Zanotti, Federica Palmeri, Venanzio Raglione, Abdolhamid Khodadadi, Camille Tabaries, Jerome Capitolis, Mathieu Prevot, Laurent Piccolo, Mahmoud Zendehdel, Roberto Flammini, Giorgio Contini   +10 more
wiley   +1 more source