Results 121 to 130 of about 2,703 (241)

New Hydrazone Derivatives Featuring Isatin and Piperazine Moieties: Synthesis, Cytotoxicity Evaluation, and Molecular Modeling Studies

Journal of Applied Toxicology, EarlyView.
ABSTRACT In this study, ten novel compounds (IPH1–IPH10) were designed by integrating three pharmacophores (isatin, piperazine, and hydrazone) commonly found in the molecular structures of anticancer agents. The target molecules were obtained by the reaction of in‐house prepared 4‐(4‐(pyridin/pyrimidin‐2‐yl)piperazin‐1‐yl)benzohydrazide with various ...
Semiha Köprü, Münevver Baran, Miyase Gözde Gündüz, Şengül Dilem Doğan   +3 more
wiley   +1 more source

Reply. [PDF]

Turk J Ophthalmol
Karataş G, Çakır A, Aday Ö, Uzundede T, Kırık F, Özoğuz AM, Özdemir H, Elçioğlu MN.   +7 more
europepmc   +1 more source

Anti‐inflammatory and cytotoxic properties of kānuka (Kunzea ericoides) subcritical water extract

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKGROUND Kānuka (Kunzea ericoides) is a medicinal plant native to New Zealand with numerous therapeutic benefits due to its rich bioactive profile. Although several in vitro studies have shown promising anti‐inflammatory activity, substantial evidence elucidating its underlying inflammatory regulatory mechanism and evaluating its cytotoxic ...
Indhuja Devadass, Simon Swift, Saeid Baroutian   +2 more
wiley   +1 more source

Real-world outcomes after switching to faricimab in treatment-resistant diabetic macular edema: A 1-year observational study with choroidal thickness assessment. [PDF]

PLoS One
Tomemori R, Mori H, Tanaka M, Kiriishi T, Omi M, Hattori Y, Oba S, Ohnaka M, Imai H.   +8 more
europepmc   +1 more source

Wheat Wild Relatives and Modern Cultivars Differ for Salt Resistance in Terms of Morpho‐Physiological Traits

Journal of Plant Nutrition and Soil Science, EarlyView.
Wheat wild relatives are untapped genetic resources from salinity and drought hit areas. This study presents differential comparative morphophysiological responses of these species and modern wheat cultivars under saline conditions. Salt resistant species produce more shoot and root biomass under saline conditions through salt exclusion and/or tissue ...
Muhammad Saqib, Riya Raj, Michael Frei
wiley   +1 more source

Validation of an Automated AI Algorithm for the Quantification of Major OCT Parameters in Retinal Vein Occlusion-Related Macular Edema. [PDF]

J Clin Med
Carnevali A, Chisari D, Gioia R, Mancini A, Borselli M, Macrì R, Lucisano A, Carnovale Scalzo G, Frizziero L, Scorcia V, Midena E.   +10 more
europepmc   +1 more source

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen, Didem Şöhretoğlu, Ayşe Kuruüzüm‐Uz   +2 more
wiley   +1 more source

Multi-scale Interaction Mechanism for Edge-Localized-Mode Suppression in the Tokamak Edge. [PDF]

Nat Commun
Li Z, Diamond PH, Chen X, Khabanov F, Xu X, Hong RJ, Chan VS, Muscatello CM, Zeng L, Yu GY, Rhodes T, McKee GR, Yan Z, Austin ME.   +13 more
europepmc   +1 more source

Autophagy Plays a Suppressive Role in Bladder Tumor Formation in an Orthotopic Mouse Model and Bladder Cancer Patient Specimens

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Autophagy plays either a suppressing or promoting role during tumor development. Clarifying the role of autophagy in bladder tumorigenesis both in vitro and in vivo is crucial for developing novel therapeutic strategies through manipulating autophagy activity.
Wan‐Ting Kuo, Chin‐Chen Pan, Yi‐Wen Liu, Nan‐Haw Chow, Hong‐Lin Cheng, Shan‐Ying Wu, Sheng‐Hui Lan, Chih‐Peng Chang, Hsiao‐Sheng Liu   +8 more
wiley   +1 more source

Minds Versus Codes: Triangulating Neurophysiological and Qualitative Responses to AI‐Generated Versus Human‐Made Video Advertisements

Psychology &Marketing, EarlyView.
ABSTRACT This experimental study compares how consumers engage with AI‐generated and human‐created advertisements, specifically examining patterns of visual attention, emotional and cognitive responses, attitudes toward AI, and whether emotional resonance fosters brand trust or future behavioral intentions.
Mariia Shitova, Agnieszka Kabalska, Ákos Varga, Ralf Wagner   +3 more
wiley   +1 more source