THE CALCULATION OF STRESS INTENSITY FACTOR STEEL OF RAILWAY WHEELS [PDF]
From an analysis of the dependence complex of carbon steel properties on structural parameters, it was found that for an isostructural state, the influence of austenite grain size on impact strength exceeds the dependence on carbon content.
Igor VAKULENKO +2 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
An interpretable stacking ensemble model for high-entropy alloy mechanical property prediction
High-entropy alloys (HEAs) have attracted significant attention due to their excellent mechanical properties and broad application prospects. However, accurately predicting their mechanical behavior remains challenging because of the vast compositional ...
Songpeng Zhao +7 more
doaj +1 more source
Numerical modeling of thermomechanical processes in heat-resistant alloys
This article presents a numerical simulation of thermomechanical processes in heat-resistant alloys. The authors develop the law of temperature distribution along the length of the physical body, which is considered as a rod of alloy EI-617. The authors
Б. Кенжегулов +3 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Structural Insights into Protein-Protein Interactions Involved in Bacterial Cell Wall Biogenesis
The bacterial cell wall is essential for survival, and proteins that participate in its biosynthesis have been the targets of antibiotic development efforts for decades.
Federica Laddomada +2 more
doaj +1 more source
Effect of Overlap Length on the Strength of Adhesive Joints of Steel Sheets
The study evaluates the shear strength of the single-lap adhesive joints made of C45 carbon steel. The influence of the overlap length on the shear strength of the adhesive joint was tested. The elongation of the samples was also tested.
Elżbieta Doluk +3 more
doaj +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
The Prediction of Yarn Elongation of Kenyan Ring-Spun Yarn using Extreme Learning Machines (ELM) [PDF]
The optimization of the manufacture of cotton yarns involves several processes, while the prediction of yarn quality parameters forms an important area of investigation. This research work concentrated on the prediction of cotton yarn elongation.
Josphat Igadwa Mwasiagi
doaj +1 more source

