Genome-wide transcription analysis of clinal genetic variation in Drosophila. [PDF]
Clinal variation in quantitative traits is widespread, but its genetic basis awaits identification. Drosophila melanogaster shows adaptive, clinal variation in traits such as body size along latitudinal gradients on multiple continents.
Blanc, E +7 more
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MEDB-41. Identifying a subgroup of patients with early childhood sonic hedgehog-activated medulloblastoma with unfavorable prognosis after treatment with radiation-sparing regimens including intraventricular methotrexate [Abstract] [PDF]
PURPOSE/METHODS: Clinical and molecular risk factors in 142 patients 3 years] 47% vs 85% [
Benesch, Martin +19 more
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The Interactions of the Largest Subunit of RNA Polymerase II with Other Cellular Proteins: a Bioinformatic Approach [PDF]
The function of a protein is governed by its interaction with other proteins inside a cell. Therefore, it is important to identify the interacting partners of a particular protein to decipher its function.
Bhaumik, Sukesh +4 more
core +3 more sources
The Elongator complex regulates hypocotyl growth in darkness and during photomorphogenesis [PDF]
The Elongator complex (hereafter Elongator) promotes RNA polymerase II-mediated transcript elongation through epigenetic activities such as histone acetylation.
Baez, Luis Alonso +10 more
core +3 more sources
A well characterized, peptide derivative of bovine lactoferrin, L12, has been shown to possess anticancer properties in multiple cell lines. However, adverse side effects in normal tissues and poor plasma kinetics that hinder the clinical effectiveness ...
Emily Thomas +2 more
doaj +1 more source
Elongator and the role of its subcomplexes in human diseases
The Elongator complex was initially identified in yeast, and a variety of distinct cellular functions have been assigned to the complex. In the last decade, several research groups focussed on dissecting its structure, tRNA modification activity and role
Monika Gaik +3 more
doaj +1 more source
Photon-Reggeon Interaction Vertices in the Nla [PDF]
We calculate the effective vertices for the quark-antiquark and the quark-antiquark-gluon production in the virtual photon - Reggeized gluon interaction.
A. M. Cooper-Sarkar +13 more
core +2 more sources
ELP1 Loss Disrupts Protein Homeostasis to Promote SHH Medulloblastoma [PDF]
Abstract Germline loss-of-function ELP1 variants were found in pediatric Sonic Hedgehog medulloblastomas.
openaire +1 more source
Brief Effect of a Small Hydrophobic Drug (Cinnarizine) on the Physicochemical Characterisation of Niosomes Produced by Thin-Film Hydration and Microfluidic Methods [PDF]
first_pagesettings Open AccessArticle Brief Effect of a Small Hydrophobic Drug (Cinnarizine) on the Physicochemical Characterisation of Niosomes Produced by Thin-Film Hydration and Microfluidic Methods by Li Key YeoOrcID,Temidayo O. B.
Chaw, Cheng +3 more
core +1 more source
First Person is a series of interviews with the first authors of a selection of papers published in Disease Models & Mechanisms, helping early-career researchers promote themselves alongside their papers.
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