Results 121 to 130 of about 18,144,236 (296)
Advanced Science, EarlyView.Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang +11 more
wiley +1 more source
Stochastic Version of EM Algorithm for Nonlinear Random Change-Point Models. [PDF]
Proc Int Conf Stat Theory Appl ICSTA, 2021 Zhang H, Manandhar B.
europepmc +1 more source
Advanced Science, EarlyView.In this research article, Mansoor and coworkers present a novel device that applies controlled mechanical stimuli to cardiomyocytes using pressure‐driven membrane deformation. By exposing cells to physiologically and pathologically relevant loading conditions, the platform reproduces distinct structural, functional and molecular responses associated ...
Haris Mansoor +11 more
wiley +1 more source
Forward and Backward Bellman Equations Improve the Efficiency of the EM Algorithm for DEC-POMDP. [PDF]
Entropy (Basel), 2021 Tottori T, Kobayashi TJ.
europepmc +1 more source
Advanced Science, EarlyView.Decoupling biological signals from unwanted variation in multi‑condition single‑cell RNA sequencing data remains challenging. CAPER disentangles condition‑associated biological effects from sample heterogeneity through matrix factorization, producing interpretable latent factors and a batch‑corrected expression matrix.
Ye Li +6 more
wiley +1 more source
A Generative Neuro‐Symbolic AI for Protein Sequence Design
Advanced Science, EarlyView.We introduce EffieDes, a neuro‐symbolic framework coupling deep learning‐based fitness landscape parameterization with exact automated reasoning. Unlike greedy sampling, EffieDes identifies sequences that globally optimize fitness while satisfying intricate design constraints.
Marianne Defresne +12 more
wiley +1 more source
Classification of disease recurrence using transition likelihoods with expectation-maximization algorithm. [PDF]
Stat Med, 2022 Jiang H, Li Q, Lin JT, Lin FC.
europepmc +1 more source
Self-organising Sensors for Wide Area Surveillance Using the Max-sum Algorithm
, 2010 In this paper, we consider the self-organisation of sensors within a network deployed for wide area surveillance. We present a decentralised coordination algorithm based upon the max-sum algorithm and demonstrate how self-organisation can be achieved ...
Jennings, Nick +2 more
core +2 more sources
StackingNet: Collective Inference Across Independent AI Foundation Models
Advanced Science, EarlyView.ABSTRACT Artificial intelligence (AI) built on large foundation models has transformed language understanding, computer vision, and reasoning, yet these systems remain isolated and cannot readily share their capabilities. Coordinating the complementary strengths of independently developed, black‐box foundation models is essential for trustworthy ...
Siyang Li +4 more
wiley +1 more source
First-Order Learning Models With the GDINA: Estimation With the EM Algorithm and Applications. [PDF]
Appl Psychol Meas, 2021 Yigit HD, Douglas JA.
europepmc +1 more source