Results 101 to 110 of about 89,316 (267)
First-Order Learning Models With the GDINA: Estimation With the EM Algorithm and Applications. [PDF]
Yigit HD, Douglas JA.
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The Bayesian Structural EM Algorithm
Appears in Proceedings of the Fourteenth Conference on Uncertainty in Artificial Intelligence (UAI1998)
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Discovery of a Potent Fluorescence Polarization Probe for Identifying USP1 Allosteric Inhibitors
This study presents the first ubiquitin‐specific protease 1 (USP1) allosteric fluoroprobe and fluorescence polarization assay, enabling the differentiation of allosteric and catalytic site inhibitors. Further, a novel class of tetrahydroisoquinoline‐based USP1 inhibitors is designed, with compound 14a (USP1 IC50 = 29.9 nM) showing strong selectivity ...
Jiawei Cheng +12 more
wiley +1 more source
Biological rhythms coordinate physiology, from genes to behavior. Study of circadian rhythms in brain tissue is constrained by limited throughput and spatial and temporal information quality. A new platform for high‐throughput, long‐term multiplexed fluorescent live imaging of circadian rhythms in brain slices is introduced.
Marco Ferrari +3 more
wiley +1 more source
EMeth: An EM algorithm for cell type decomposition based on DNA methylation data. [PDF]
Zhang H, Cai R, Dai J, Sun W.
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Phase‐resolved experiments and atomistic simulations reveal asynchronous ordering behaviors in a eutectic high‐entropy alloy during isothermal annealing. Distinct defect transport mechanisms are identified in coexisting B2 and BCC phases, showing that vacancy and interstitial mediated diffusion governs phase‐dependent thermal stability.
Huiwen Yao +5 more
wiley +1 more source
EM algorithm for mixture of skew-normal distributions fitted to grouped data. [PDF]
Teimouri M.
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A metasurface‐enabled ultrasonic platform achieves precise multi‐focal control through biological barriers, real‐time physiology‐driven modulation, and simultaneous wireless power and data transmission. By unifying wavefront engineering, closed‐loop feedback, and acoustic communication, this work establishes key enabling technologies toward scalable ...
Chuanxin Zhang +3 more
wiley +1 more source
Stochastic EM algorithm for generalized exponential cure rate model and an empirical study. [PDF]
Davies K, Pal S, Siddiqua JA.
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On the Convergence Properties of the EM Algorithm
Two convergence aspects of the EM algorithm are studied: (i) does the EM algorithm find a local maximum or a stationary value of the (incomplete-data) likelihood function? (ii) does the sequence of parameter estimates generated by EM converge? Several convergence results are obtained under conditions that are applicable to many practical situations ...
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