Results 61 to 70 of about 104,844 (357)

Projected WIMP sensitivity of the LUX-ZEPLIN dark matter experiment [PDF]

open access: yes, 2020
LUX-ZEPLIN (LZ) is a next-generation dark matter direct detection experiment that will operate 4850 feet underground at the Sanford Underground Research Facility (SURF) in Lead, South Dakota, USA. Using a two-phase xenon detector with an active mass of 7
Akerib, DS   +99 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Contribution of Emanationist Philosophy to the Development of Environmental Conservation

open access: yesAn-Nida'
The global ecological crisis demonstrates that contemporary ethical frameworks have been insufficient in mitigating the accelerating rate of environmental degradation.
Rifqah Najwa Azizah   +3 more
doaj   +1 more source

Education Versus Creativity: the Origins of Demystification

open access: yesОбразование и наука, 2015
The paper is devoted to the comparative analysis of the archaic and modern options for understanding creativity, carried out with the involvement of the theological instruments.
A. G. Kislov
doaj   +1 more source

Mechanism of endocarp-imposed constraints of germination of Lannea microcarpa seeds [PDF]

open access: yes, 2008
Lannea microcarpa, a multipurpose tree species from the dry African savanna, sheds seeds that often display inhibition of germination. The underlying mechanism was investigated using seeds processed from fully matured fruits collected from natural stands
Golovina, E.A., Hoekstra, F.A., Neya, O.
core   +2 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Symbolic Emanations of God’s Great Title in Monotheism figures in the Islamic Art and Architecture Works [PDF]

open access: yesنگره, 2017
The main issue is to study the quality of semantic implications of God’s great title in Islamic art and architecture works. The purpose is to gain the secret behind immortality of symbolic language of forms, figures, patterns, and structures of Islamic ...
fatemeh akbari
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

In the Thick of Things [PDF]

open access: yes, 2016
Short introduction to the V2 publication of "The War of Appearances: Transparency, Opacity, Radiance" (2016). An anthology with Matteo Pasquinelli, Luciana Parisi, Graham Harman, Tomas Saraceno, René ten Bos, Tim Morton, and many ...
Brouwer, Joke   +2 more
core  

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

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