Results 41 to 50 of about 1,308,491 (270)

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Radon Emanation Techniques and Measurements for LZ [PDF]

open access: yes, 2022
Radon emanation was projected to account for $>50$% of the electron recoil background in the WIMP region of interest for the LUX-ZEPLIN (LZ) experiment.
Chott, N. I., Schnee, R. W.
core  

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

open access: yesFEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Emanation Graph: A Plane Geometric Spanner with Steiner Points [PDF]

open access: yes, 2022
An emanation graph of grade $k$ on a set of points is a plane spanner made by shooting $2^{k+1}$ equally spaced rays from each point, where the shorter rays stop the longer ones upon collision.
Rahmati, Zahed   +2 more
core   +1 more source

CORRELATION OF RADON AND SEISMIC ACTIVITY IN THE BAIKAL RIFT ZONE ACCORDING TO EMANATION MONITORING DATA

open access: yesГеодинамика и тектонофизика
Long series of the emanation monitoring organized at Tyrgan (2018–2023), Buguldeika (2020–2023) and Maksimikha (2022–2023) stations in the central part of the Baikal Region (the Eastern Siberia) are studied to reveal the relationship of the subsurface ...
K. Zh. Seminsky, А. А. Bobrov
doaj   +1 more source

Building and characterisation of a radon emanation source using a historical watch painted with radioluminescent paint containing radium [PDF]

open access: yes
Conducting experiments with 222Rn not always requires a radon emanation source traceable to primary standards, often it is sufficient to use a well characterised radium source.
Grapentin, Raphael
core   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons   +33 more
wiley   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani   +10 more
wiley   +1 more source

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird   +9 more
wiley   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe   +7 more
wiley   +1 more source

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