Results 41 to 50 of about 284,235 (303)

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh   +5 more
wiley   +1 more source

Harnessing Large‐Scale Multi‐Omics Data for Risk Prediction and Deep Phenotyping of Valvular Heart Diseases in the General Population

open access: yesAdvanced Science, EarlyView.
Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang   +10 more
wiley   +1 more source

Diagnostic Accuracy of Size‐Based Preoperative CT Assessment for Predicting Lymph Node Metastasis in Colon Cancer: A Systematic Review and Meta‐Analysis

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Preoperative CT based on lymph node size shows moderate accuracy for detecting nodal metastasis in colon cancer. In this meta‐analysis of 29 studies (5,634 patients), pooled sensitivity and specificity were 0.69 and 0.66. Size‐based CT alone has limited value for clinical decision‐making.
Yuji Takayama   +4 more
wiley   +1 more source

Chronic Rhinosinusitis and Nasal Polyps in Eosinophilic Granulomatosis With Polyangiitis: A Scoping Review

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) is one of the most common manifestations of eosinophilic granulomatosis with polyangiitis (EGPA), often preceding the diagnosis of systemic vasculitis by several years. The sinonasal presentation of EGPA typically resembles CRS with nasal polyps (CRSwNP), making it clinically indistinguishable from those
Alisha Sharma   +12 more
wiley   +1 more source

Bibliometric analysis of cardiovascular disease research activity in the Arab world

open access: yesGlobal Cardiology
Background: In the Arab world, the prevalence of chronic noncommunicable diseases – such as cancer, diabetes, chronic respiratory conditions, and cardiovascular diseases – has increased.
Hussein H. Khachfe, Marwan M. Refaat
doaj   +1 more source

Scoping literature review: Comparing MRI tractography methods for optic radiation analysis

open access: yesThe Anatomical Record, EarlyView.
Abstract Accurate tractography mapping of the optic radiations is essential to avoiding post‐operative visual field deficits in patients undergoing temporal lobe surgery. This literature review highlights the current landscape of MRI tractography methods that are used to delineate the optic radiations (ORs), with a particular focus on the anterior ...
Hriday Sahni   +3 more
wiley   +1 more source

Searching for Adverse Effects in MEDLINE and EMBASE Requires a Combined Approach for Efficient Retrieval

open access: yesEvidence Based Library and Information Practice, 2006
A review of: Golder, Su, Heather M. McIntosh, Steve Duffy, and Julie Glanville. “Developing Efficient Search Strategies to Identify Reports of Adverse Effects in MEDLINE and EMBASE.” Health Information & Libraries Journal 23.1 (Mar.
Marcy L. Brown
doaj   +1 more source

Intra‐articular Orthobiologics Show Statistically but Not Clinically Meaningful Improvements Compared With Viscosupplementation in Knee Osteoarthritis: A Network Meta‐analysis of Randomized Controlled Trials

open access: yesArthroscopy, EarlyView.
Purpose To evaluate the comparative effectiveness of intra‐articular platelet‐rich plasma (PRP), stromal vascular fraction (SVF), bone marrow aspirate concentrate (BMAC), umbilical cord‐derived mesenchymal stem cell (UC‐MSC), and hyaluronic acid (HA) for pain relief and functional improvement in patients with knee osteoarthritis through network meta ...
Joo Hyung Han   +5 more
wiley   +1 more source

New Search Strategies Successfully Optimize Retrieval of Clinically Sound Treatment Studies in EMBASE. A review of: Wong, Sharon S‐L, Nancy L. Wilczynski, and R. Brian Haynes. “Developing Optimal Search Strategies for Detecting Clinically Sound Treatment Studies in EMBASE.” Journal of the Medical Library Association 94.1 (Jan. 2006): 41‐47. 14 May 2007 http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1324770.

open access: yesEvidence Based Library and Information Practice, 2007
Objective – To develop and test the sensitivity and specificity, precision andaccuracy of search strategies to retrieve clinically sound treatment studies in the EMBASE database.Design – Analytical study.Setting – Methodologically sound studies of ...
John Loy
doaj  

Lateral Extra‐articular Procedures Decrease Rates of Graft Failure and Positive Pivot Shift in Primary Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta‐analysis

open access: yesArthroscopy, EarlyView.
Purpose To synthesize the existing literature on clinical outcomes and patient‐reported outcome measures following primary anterior cruciate ligament reconstruction (ACLR) and lateral extra‐articular procedures (LEAP) in randomized controlled trials, whereas also determining ceiling effects for the patient‐reported outcome measures utilized.
Matthew Macciacchera   +5 more
wiley   +1 more source

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