Results 31 to 40 of about 2,735,473 (307)

Computational 4D-OCM for label-free imaging of collective cell invasion and force-mediated deformations in collagen

open access: yesScientific Reports, 2021
Traction force microscopy (TFM) is an important family of techniques used to measure and study the role of cellular traction forces (CTFs) associated with many biological processes. However, current standard TFM methods rely on imaging techniques that do
Jeffrey A. Mulligan   +4 more
doaj   +1 more source

Study the path planning of intelligent robots and the application of blockchain technology

open access: yesEnergy Reports, 2022
With the improvement of China’s science and technology, robot technology has been widely developed and applied. The most significant feature of China’s intelligent robot technology advancement is the combination of embedded systems and robotics. Embedded
Jiaofei Huo, Bin Pan
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Data on force-dependent structural changes of chromatin fibers measured with magnetic tweezers

open access: yesData in Brief, 2014
The compaction of chromatin fibers regulates the accessibility of embedded DNA, highly associated with transcriptional activities [1]. Single molecule force spectroscopy has revealed the great details of the structural changes of chromatin fibers in the ...
Fan-Tso Chien
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Sample-prototype optimal transport-based universal domain adaptation for remote sensing image classification

open access: yesComplex & Intelligent Systems
In recent years, there is a growing interest in domain adaptation for remote sensing image scene classification, particularly in universal domain adaptation, where both source and target domains possess their unique private categories.
Xiaosong Chen   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

A Soft Anthropomorphic & Tactile Fingertip for LowCost Prosthetic & Robotic Applications

open access: yesEAI Endorsed Transactions on Pervasive Health and Technology, 2018
Nowadays, prosthetic and robotic hands have reached an amazing dexterity and grasping capability. However, to enhance a proper tactile 'experience', dexterity should be supported by proper sensation of daily life objects which such devices are supposed ...
E. L. Secco, C. Moutschen
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

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