Results 41 to 50 of about 189,796 (264)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Parallel Fin Ray Soft Gripper with Embedded Mechano-Optical Force Sensor
Applied SciencesThe rapid advancement in soft robotics over the past decade has driven innovation across the industrial, medical, and agricultural sectors. Among various soft robotic designs, Fin Ray-inspired soft grippers have demonstrated remarkable adaptability and ...
Eduardo Navas +3 more
doaj +1 more source
Validation of Instrumented Football Shoes to Measure On-Field Ground Reaction Forces
Sensors, 2022 Ground reaction forces (GRF) have been widely studied in football to prevent injury. However, ambulatory tools are missing, posing methodological limitations.
Alexandre Karamanoukian +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Subway Embedded Track Geometric Irregularity Safety Limits
Chinese Journal of Mechanical Engineering, 2021 A coupling dynamic model of a subway train and an embedded track is established to study the safety limits of track irregularities. The simulated vehicle system was a 74-degrees of freedom multi-rigid body model, and the rail was a Timoshenko beam.
Yuxiang Zhang +3 more
doaj +1 more source
Buildings, 2023 Anchorage force comprises bond force and bearing pressure when headed bars are used. Pull-out tests were conducted on 120 concrete specimens to derive a method for calculating the bond force for reinforcement in straight anchor sections at the yield ...
Tianming Miao +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Influence of built-in strain sensor on the mechanical properties of asphalt mixture
工程科学学报The pursuit of intelligence and smartness in road infrastructure is critical for the advancement of road engineering. Embedded strain sensors serve as a vital tool for sensing strain within pavement structures.
Li LIU +5 more
doaj +1 more source
Risk of forced labour embedded in the US fruit and vegetable supply
Nature Food, 2021 Sustainable food consumption studies have largely focused on promoting human health within ecological limits. Less attention has been paid to social sustainability, in part because of limited data and models. Globally, agriculture has one of the highest incidences of forced labour, with exploitative conditions enabled by low margins, domestic labour ...
Nicole Tichenor Blackstone +4 more
openaire +2 more sources
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source