Results 61 to 70 of about 203,720 (301)
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Quantitative Nano-characterization of Polymers Using Atomic Force Microscopy
CHIMIA, 2017 The present article offers an overview on the use of atomic force microscopy (AFM) to characterize the nanomechanical properties of polymers. AFM imaging reveals the conformations of polymer molecules at solid– liquid interfaces.
Milad Radiom +9 more
doaj +1 more source
Horizontal vibration response analysis of piles in liquefied soil under Winkler foundation model
Rock and Soil Mechanics, 2020 By considering the condition of vertical load, the soil after complete liquefaction is regarded as fluid, and the pile foundation is equivalent to the Euler-Bernoulli beam model.
XIONG Hui, YANG Feng
doaj +1 more source
Advances in Mechanical Engineering, 2018 The cutting force generated during the cutting process affects the quality of the workpieces and tool wear. Accurate real-time monitoring of cutting forces plays an important role in the study of cutting mechanism and machining quality improvement.
Xuerui Li +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Dowel Behavior of Rebars in Small Concrete Block for Sliding Slab Track on Railway Bridges
Advances in Materials Science and Engineering, 2018 In recent years, several studies have investigated the sliding slab track for railway bridges. In the design of sliding slab tracks, one of the most important considerations is to evaluate the shear capacity of the lateral supporting concrete blocks in ...
Seong-Cheol Lee +3 more
doaj +1 more source
Large Oil and Gas industry text dataset from Norwegian , UK and Dutch public oil and gas documents
<p>This is a large dataset of extracted text from public Oil and gas documents that was prepared in the run up to the FORCE 2023 Large Languagel model Hackathon in Stavanger, Norway</p> <p>The dataset is uninque since it contains ...
FORCE NETWORK Group
core +1 more source
, 2007 In this paper, the possible error sources of the composite natural frequencies due to modeling the shape memory alloy (SMA) wire as an axial force or an elastic foundation and anisotropy are discussed.
Zhao, YP (reprint author), Chinese Acad Sci, Inst Mech, State Key Lab Nonlinear Mech, Beijing 100080, Peoples R China. +2 more
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Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source