Results 71 to 80 of about 2,827,837 (350)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

XinuPi3: Teaching Multicore Concepts Using Embedded Xinu [PDF]

, 2017
As computer platforms become more advanced, the need to teach advanced computing concepts grows accordingly. This paper addresses one such need by presenting XinuPi3, a port of the lightweight instructional operating system Embedded Xinu to the Raspberry
Bansal, Priva, Brylow, Dennis, Latinovich, Rade, Lazar, Tom, McGee, Patrick J.   +4 more
core   +1 more source

Traffic Flow Data Prediction Using Residual Deconvolution Based Deep Generative Network

IEEE Access, 2019
Traffic flow prediction is quite crucial for estimating the future traffic states, efficient and accurate prediction models greatly contribute to the smooth traffic of road networks.
Di Zang, Yang Fang, Zhihua Wei, Keshuang Tang, Jiujun Cheng   +4 more
doaj   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Density-functional embedding using a plane-wave basis

, 2009
The constrained electron density method of embedding a Kohn-Sham system in a substrate system (first described by P. Cortona, Phys. Rev. B {\bf 44}, 8454 (1991) and T.A. Wesolowski and A. Warshel, J. Phys.
A. Lembarki, A.E. DePristo, A.J. Fisher, A.J. Thakkar, C. Herring, D. M. Bird, D.J. Lacks, E. Chacón, E. Hernández, E. Smargiassi, E.V. Ludena, E.W. Pearson, F. Perrot, G. Zumbach, G.P. Kerker, H. Lee, H. Ou-Yang, J. R. Trail, J.A. Anata, J.A. White, J.E. Inglesfield, J.P. Perdew, J.P. Perdew, J.P. Perdew, L. Goodwin, L. Vitos, L.J. Bartolotti, L.W. Wang, M.C. Payne, N. Govind, P. Cortona, P. García-González, P. Ordejon, R. G. Parr, R. M. Dreizler, R.O. Jones, S. Baroni, S. Goedecker, S. Goedecker, S. Liu, S. Watson, T.A. Wesolowski, T.A. Wesolowski, T.A. Wesolowski, T.A. Wesolowski, T.L. Gilbert, U. Gutdeutsch, U. Gutdeutsch, V. Shah, W. Kohn, W. Kohn, W. Yang, W. Yang, Y.A. Wang   +53 more
core   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Implementation of packaged integrated antenna with embedded front end for Bluetooth applications [PDF]

, 2008
The design, integration and realization of system in enhanced package approach towards fully functional system level integration by using a compact Bluetooth USB dongle as the demonstrator is presented here.
Chee-Parng, C., Kuruveettil, H., Popov, A.P., Rotaru, M., Rui, Y., Ying, L.Y.   +5 more
core   +1 more source

Embedded Patient Monitoring System

International Journal of Power Electronics and Drive Systems (IJPEDS), 2019
<p>ICU remains for Intensive Care Unit, a place in the recuperating office where wiped out patients are checked eagerly. Commonly, the patient-staff extent is low and the LIFE-SAVING EQUIPMENT used is outstandingly bleeding edge Generally ICU is a healing facility for course of action of genuine nursing and remedial consideration of essentially ...
Jayanna Kanchikere, A.K. Ghosh, Kalyankumar   +2 more
openaire   +4 more sources

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Equilibrium and Dynamical Evolution of Self-Gravitating System Embedded in a Potential Well

, 2011
Isothermal and self-gravitating systems bound by non-conducting and conducting walls are known to be unstable if the density contrast between the center and the boundary exceeds critical values.
Aarseth, Aarseth, Aarseth, Aarseth, Antonov, Binney, Binney, Chavanis, Chavanis, Chavanis, Chavanis, Cohn, de Vega, de Vega, Dehnen, Eckart, Figer, Hachisu, Heggie, Heggie, Horowitz, Hyung Mok Lee, Ilsang Yoon, Inagaki, Jongsuk Hong, Joshi, Katz, Katz, Katz, King, Lee, Lee, Lynden Bell, Lynden Bell, Mo, Padmanabhan, Padmanabhan, Spitzer, Taruya, Taruya, Taruya, Tsallis, van der Marel, Velazquez   +43 more
core   +1 more source