Results 101 to 110 of about 23,776,920 (366)

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Kalman Filter With Dynamical Setting of Optimal Process Noise Covariance

IEEE Access, 2017
We propose a dynamical way to set the process error covariance matrix (Q) for a constant velocity (CV) model Kalman filter. We are able to achieve the best possible solution for the estimated state, in the sense of forecast error, while significantly ...
Gabriel F. Basso, Thulio Guilherme Silva De Amorim, Alisson V. Brito, Tiago P. Nascimento   +3 more
doaj   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Vehicle Detection Based on Probability Hypothesis Density Filter

Sensors, 2016
In the past decade, the developments of vehicle detection have been significantly improved. By utilizing cameras, vehicles can be detected in the Regions of Interest (ROI) in complex environments.
Feihu Zhang, Alois Knoll
doaj   +1 more source

Deep Homography for License Plate Detection

Information, 2020
The orientation of plate images in license plate recognition is one of the factors that influence its accuracy. In particular, tilted plate images are harder to detect and recognize characters with than aligned ones.
Hojin Yoo, Kyungkoo Jun
doaj   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

FLEET: When Time-Bounded Communication Meets High Energy-Efficiency

IEEE Access, 2019
With the advent of low-cost, embedded sensor-actuator devices, the applications of cyber-physical systems have spread multi-fold in domains like infrastructure, manufacturing, automation, etc. Wireless sensor-actuator networks (WSANs) act as the backbone
Chayan Sarkar, R. Venkatesha Prasad, Koen Langendoen   +2 more
doaj   +1 more source

AVATAR: A Framework to Support Dynamic Security Analysis of Embedded Systems' Firmwares

Network and Distributed System Security Symposium, 2014
In this paper we present Avatar, a framework that enables complex dynamic analysis of embedded devices by orchestrating the execution of an emulator together with the real hardware.
Jonas Zaddach, L. Bruno, Aurélien Francillon, D. Balzarotti   +3 more
semanticscholar   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Digital Light Processing of 2D Lattice Composites for Tunable Self‐Sensing and Mechanical Performance

Advanced Engineering Materials, EarlyView., 2023
The study presents the mechanical and in situ sensing performance of digital light processing‐enabled 2D lattice nanocomposites under monotonic tensile and repeated cyclic loading, and provides guidelines for the design of architectures suitable for strain sensors and smart lightweight structures.
Omar Waqas Saadi, Mohammed Ayaz Uddin, Andreas Schiffer, Shanmugam Kumar   +3 more
wiley   +1 more source