Results 51 to 60 of about 10,189,459 (300)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

CESCA Newsletter

open access: yes, 2013
On 15 March 2013, the Center for Embedded Systems for Critical Applications is organizing a public event to present its ongoing research projects.. The theme of the symposium is Embedded Security.
Virginia Tech. Center for Embedded Systems for Critical Applications
core   +1 more source

HVAS: Detection of Vegetation Height near Electric Transmission Lines Using Deep Learning and Satellite Images [PDF]

open access: yesISPRS Annals of the Photogrammetry, Remote Sensing and Spatial Information Sciences
Vegetation encroachment near power transmission lines poses risks such as outages, fires, and increased maintenance costs. This study presents a method for estimating vegetation height using public satellite imagery and convolutional neural networks ...
J. Majin Erazo   +12 more
doaj   +1 more source

The Discipline of Embedded Systems Design [PDF]

open access: yesComputer, 2007
The wall between computer science and electrical engineering has kept the potential of embedded systems at bay. It is time to build a new scientific foundation with embedded systems design as the cornerstone, which will ensure a systematic and even-handed integration of the two fields.
Thomas A. Henzinger, Joseph Sifakis
openaire   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

DMS: Dynamic Model Scaling for Quality-Aware Deep Learning Inference in Mobile and Embedded Devices

open access: yesIEEE Access, 2019
Recently, deep learning has brought revolutions to many mobile and embedded systems that interact with the physical world using continuous video streams.
Woochul Kang, Daeyeon Kim, Junyoung Park
doaj   +1 more source

The Benefits and Costs of Netlist Randomization Based Side-Channel Countermeasures: An In-Depth Evaluation

open access: yesJournal of Low Power Electronics and Applications, 2022
Exchanging FPGA-based implementations of cryptographic algorithms during run-time using netlist randomized versions has been introduced recently as a unique countermeasure against side channel attacks.
Ali Asghar   +2 more
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

AI Concepts for System of Systems Dynamic Interoperability

open access: yesSensors
Interoperability is a central problem in digitization and System of Systems (SoS) engineering, which concerns the capacity of systems to exchange information and cooperate.
Jacob Nilsson   +5 more
doaj   +1 more source

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