Results 71 to 80 of about 10,189,459 (300)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

The Embedded Systems Design Challenge [PDF]

open access: yes, 2006
We summarize some current trends in embedded systems design and point out some of their characteristics, such as the chasm between analytical and computational models, and the gap between safety-critical and best-effort engineering practices. We call for a coherent scientific foundation for embedded systems design, and we discuss a few key demands on ...
Henzinger, T. A., Sifakis, J.
openaire   +3 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Hierarchical Scheduler with Adaptive Time-Budget Reallocation for Time-Triggered Edge-Fog-Cloud Architectures

open access: yesFuture Internet
The lack of determinism restricts the integration of safety-critical applications into Edge–Fog–Cloud (EFC) architectures. Existing EFC schedulers are typically designed for dynamic, best-effort operation based on unmanaged resource allocation and ...
Omar Hekal   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Supporting symmetric 128-bit AES in networked embedded systems: An elliptic curve key establishment protocol-on-chip [PDF]

open access: yes, 2007
The secure establishment of cryptographic keys for symmetric encryption via key agreement protocols enables nodes in a network of embedded systems and remote agents to communicate securely in an insecure environment.
MIGUEL MORALES SANDOVAL
core  

Embedded Systems Software Architecture

open access: yes, 2013
Embedded Systems are the dominate type of computer systems today; they span a range from small systems that include a simple platform integrated with sensors and actuators, to large distributed systems consisting of hundreds, or possibly thousand ...
Crnkovic, Ivica,, Stafford, Judith
core   +1 more source

CESCA Newsletter

open access: yes, 2012
The projects carried out by CESCA Faculty and their students represent a valuable resource of intellectual property. CESCA has a model in place that helps industry to benefit from this knowhow and these results - CESCA's Industry Affiliate Program (IAP).
Virginia Tech. Center for Embedded Systems for Critical Applications
core   +1 more source

Embeddings of Resolvable Triple Systems

open access: yesJournal of Combinatorial Theory, Series A, 2000
A resolvable triple system of order \(v\) can appear as a subsystem of a resolvable triple system of order \(u\) when \(u=v\) or \(u\geq 3v\), and \(u\) and \(v\) are both multiples of \(3\). When the index is odd, \(u\) and \(v\) must also be odd; and when the index is singly even, \(v\) cannot be \(6\) as no resolvable triple system of order \(6 ...
Hao Shen, Yizhu Wang
openaire   +3 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

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