Results 91 to 100 of about 525,882 (299)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

The production of relative clauses in Italian-speaking children with DLD

open access: yesIsogloss
Children with Developmental Language Disorder (DLD) have been shown to struggle with the acquisition of complex structures requiring structural embedding and movement of a sentential element from its original position. This study examines the production
Fabrizio Arosio   +2 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

KRAS Genotyping of Paraffin-Embedded Colorectal Cancer Tissue in Routine Diagnostics [PDF]

open access: bronze, 2009
Wilko Weichert   +11 more
openalex   +1 more source

Feasibility pilot of an adapted parenting program embedded within the Thai public health system [PDF]

open access: gold, 2021
Amalee McCoy   +8 more
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

A protocol for high-quality sectioning for tree-ring anatomy

open access: yesFrontiers in Plant Science
Quantitative wood anatomy (QWA), which involves measuring wood cell anatomical characteristics commonly on dated tree rings, is becoming increasingly important within plant sciences and ecology.
Marina V. Fonti   +19 more
doaj   +1 more source

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