Results 91 to 100 of about 1,342,763 (314)
Universal Scaling of Thin Current Sheets
Geophysical Research Letters, 2020 Thin current sheets (TCSs) with thicknesses about ion Larmor radii are widespread in space. It is important to describe their equilibrium structure allowing them to store and then explosively release the accumulated free energy.
L. M. Zelenyi +4 more
doaj +1 more source
Local procrustes for manifold embedding: a measure of embedding quality and embedding algorithms [PDF]
Machine Learning, 2009 We present the Procrustes measure, a novel measure based on Procrustes rotation that enables quantitative comparison of the output of manifold-based embedding algorithms (such as LLE (Roweis and Saul, 2000) and Isomap (Tenenbaum et al, 2000)). The measure also serves as a natural tool when choosing dimension-reduction parameters.
Yair Goldberg, Ya'acov Ritov
openaire +3 more sources
Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
wiley +1 more source
Molecular Oncology, EarlyView.mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo +8 more
wiley +1 more source
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
An Optimal Skorokhod Embedding for Diffusions
, 2002 Given a Brownian motion $B_t$ and a general target law $\mu$ (not necessarily centered or even integrable) we show how to construct an embedding of $\mu$ in $B$.
Cox, A. M. G., Hobson, D. G.
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Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
GDRMA: Graph Neural Networks for Document Retrievals With Mean Aggregation
IEEE AccessWith the proliferation of cloud services and high-capacity hard drives, the volume of stored document data is rapidly increasing. Consequently, large-scale document retrieval tasks have been attracting significant attention.
Shigeru Maya
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Hash Embeddings for Efficient Word Representations
, 2017 We present hash embeddings, an efficient method for representing words in a continuous vector form. A hash embedding may be seen as an interpolation between a standard word embedding and a word embedding created using a random hash function (the hashing ...
Hansen, Jonas Meinertz +2 more
core
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source