Results 41 to 50 of about 1,136 (216)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Journal of the Civil Engineering Forum, 2022 The embedment length influences the adhesion between the cast iron material and the concrete. The concrete's compression strength also contributes to an increase in bond strength.
Anis Rosyidah +2 more
doaj +1 more source
[1988] Proceedings. Third Annual Information Symposium on Logic in Computer Science, 1989 A categorical generalisation of the notion of domain, used in denotational semantics, is proposed. The generalized domain is a category of ``structures'' and embeddings which is closed under directed colimits and such that any ``structure'' is the directed colimit of its finite substructures.
openaire +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
PILE SETTLEMENT INDUCED FROM SOIL MOVEMENT DUE TO BREAKDOWN OF RETAINING WALL
Acta Polytechnica, 2020 Very few studies measured the settlement of retaining wall supported piles foundation under a soil movement. This study explores the pile settlement induced from the sudden breakdown of a closely located retaining wall using a small-scale experimental ...
Rajesh Prasad Shukla
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
CoRR, 2018 Classic grammars and regular expressions can be used for a variety of purposes, including parsing, intent detection, and matching. However, the comparisons are performed at a structural level, with constituent elements (words or characters) matched exactly. Recent advances in word embeddings show that semantically related words share common features in
David Wingate +3 more
openaire +2 more sources
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Node Embeddings via Neighbor Embeddings
Trans. Mach. Learn. Res.Accepted to Transactions of Machine Learning Research (TMLR)
Jan Niklas Böhm +5 more
openaire +4 more sources