Results 51 to 60 of about 1,136 (216)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Embedded vortices [PDF]

open access: yesPhysical Review D, 1998
We present a discussion of embedded vortices in general Yang-Mills theories. The origin of a family structure of solutions is shown to be group theoretic in nature and a procedure for its determination is developed. Vortex stability can be quantified into three types: Abelian topological stability, non-Abelian topological stability, and dynamical ...
Lepora, Nathan F., Davis, Anne-Christine
openaire   +2 more sources

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

open access: yesFEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia   +6 more
wiley   +1 more source

In Bed with the Library: A Critical Exploration of Embedded Librarianship at the City University of New York

open access: yesCommunications in Information Literacy, 2017
This project considers the efficacy and scalability of embedded librarianship initiatives within the City University of New York (CUNY) library system and presents findings of an original research study conducted in 2015.
Nora Almeida, Julia Pollack
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Investigation of mechanical properties and elucidation of factors affecting wood-based structural panels under embedment stress with a circular dowel i: analysis of the influence of various conditions on the embedment properties

open access: yesJournal of Wood Science, 2023
Embedment properties are vital to timber structural designs, and many types of wood-based structural panels have been developed for diverse uses. Comprehensive and systematic studies regarding the embedment properties of wood-based structural panels are ...
Ryutaro Sudo   +2 more
doaj   +1 more source

Progressive embedding [PDF]

open access: yesACM Transactions on Graphics, 2019
Tutte embedding is one of the most common building blocks in geometry processing algorithms due to its simplicity and provable guarantees. Although provably correct in infinite precision arithmetic, it fails in challenging cases when implemented using floating point arithmetic, largely due to the induced exponential area changes.
Hanxiao Shen   +3 more
openaire   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Effect of Thermal Modification of Spruce Wood on Nails Embedment Strength [PDF]

open access: yesPro Ligno, 2018
Nails represent the easiest and most common method to connect timber members, but, since joints and connections frequently represent the weakest points in timber structures, they need special attention.
Mirko KARIZ   +2 more
doaj  

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