Results 91 to 100 of about 439,570 (294)

SAR Miniatures: Physical Scale Models as Immersive Prototypes for Spatially Augmented Environments

Designs
This paper explores the use of physical scale models as immersive prototypes in the design and development of Spatial Augmented Reality (SAR) environments.
Omar Martinez Gasca, Lucas Van Dorpe, Ivo Dewit, Lukas Van Campenhout   +3 more
doaj   +1 more source

Intercorporeality and Interaffectivity

Phenomenology and Mind, 2017
According to phenomenological and enactive approaches, human sociality does not start from isolated individuals, but from intercorporeality and interaffectivity.
Thomas Fuchs
doaj   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

A Human–System Coupling Framework for Collective Synchronization Through Computational Interpretation of Bodily Energy

Applied Sciences
This paper proposes a human–system coupling framework for understanding interactive environments in which embodied human activity is continuously translated into perceptual feedback through computational systems.
Hsuan-Cheng Lin
doaj   +1 more source

An embodied communication system with avatar-shadow’s color expressions based on an interaction-activated communication model in voice communication

Nihon Kikai Gakkai ronbunshu, 2019
Shadows play an important role in the effects of three-dimension and the enhancement of reality in virtual space. On the other hand, addition of color change in human interaction and communication is effective for enhancing expressions such as affects ...
Yoshihiro SEJIMA, Yutaka ISHII, Tomio WATANABE   +2 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Robot motion characteristics for embodied interaction with humans using upper arm

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2020
Humans establish embodied interactions, such as bows and handshakes, when they first meet. Through these embodied interactions, it is believed that humans construct a relationship that is emotionally acceptable to each other.
Mitsuru JINDAI, Shunsuke OTA, Toshiyuki YASUDA, Tohru SASAKI   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Free-Hand Input and Interaction in Virtual Reality Using a Custom Force-Based Digital Thimble

Applied Sciences
This article presents the Digital Thimble, an index-finger-wearable device designed for free-hand interactions in virtual reality (VR) by varying the touch contact force on a surface. It contains an optical mouse sensor for tracking and a pressure sensor
Tafadzwa Joseph Dube, Ahmed Sabbir Arif
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source