Results 101 to 110 of about 439,570 (294)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Walking with Gail

open access: yesSocial Interaction
By analysing the movements through space of a famous conversation analyst delivering a well-known lecture, this paper reveals the creative construction of space within the social and physical constraints of the lecture hall, and in so doing contributes ...
Darren Reed   +2 more
doaj   +1 more source

Identity, community and embodiment: Chopper’s tattoo tour [PDF]

open access: yes, 2011
Heavy Metal fans have a unique style of dress, music and interaction via which a sub-cultural community is formed and maintained. This article explores how this community is embodied through tattoos and the display of cultural symbols associated with the
Hodgetts, Darrin   +2 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Speech-driven embodied entrainment character system with a voice back-channel

open access: yesNihon Kikai Gakkai ronbunshu, 2019
We have already developed a speech-driven embodied entrainment CG character system called “InterActor” which generates communicative motions and actions such as nods for entrained interaction from speech rhythm based on only voice input.
Makiko NISHIDA   +2 more
doaj   +1 more source

Artificial Life in Quantum Technologies

open access: yes, 2016
We develop a quantum information protocol that models the biological behaviors of individuals living in a natural selection scenario. The artificially engineered evolution of the quantum living units shows the fundamental features of life in a common ...
Alvarez-Rodriguez, U.   +3 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

The Content-Specific Display: Between Medium and Metaphor

open access: yesDesigns
This paper examines the current generation of displays, as found primarily in smartphones, laptops and tablet computers, from an interaction design perspective.
Lukas Van Campenhout   +2 more
doaj   +1 more source

Non-visual Virtual Reality: Considerations for the Pedagogical Design of Embodied Mathematical Experiences for Visually Impaired Children

open access: yesEducational Technology & Society, 2021
Digital developments that foreground the sensory body and movement interaction offer new ways of engaging with mathematical ideas. Theories of embodied cognition argue for the important role of sensorimotor interaction in underpinning cognition.
Nikoleta Yiannoutsou   +2 more
doaj  

Designing and Implementing Embodied Agents: Learning from Experience [PDF]

open access: yes, 2001
In this paper, we provide an overview of part of our experience in designing and implementing some of the embodied agents and talking faces that we have used for our research into human computer interaction.
Heylen, D.K.J., Nijholt, A.
core   +2 more sources

Home - About - Disclaimer - Privacy