Results 81 to 90 of about 439,570 (294)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Emphatic agents to reduce user frustration: The effects of varying agent characteristics [PDF]
, 2006 There is now growing interest in the development of computer systems which respond to users’ emotion and affect. We report three small scale studies (with a total of 42 participants) which investigate the extent to which affective agents, using ...
Hone, KS
core
Pragmatism and the pragmatic turn in cognitive science [PDF]
, 2016 This chapter examines the pragmatist approach to cognition and experience and provides some of the conceptual background to the “pragmatic turn” currently underway in cognitive science.
Menary, Richard
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Turn-by-wire: Computationally mediated physical fabrication [PDF]
, 2019 Advances in digital fabrication have simultaneously created new capabilities while reinforcing outdated workflows that constrain how, and by whom, these fabrication tools are used.
Gupta Sidhant +6 more
core +1 more source
Interactional Expertise and Embodiment
, 2016 In Part 1 of this paper, I introduce the idea of interactional expertise while in Part 2, I focus on its implications for philosophical theories of the importance of the body in forming our conceptual world. I argue that the way philosophers have dealt with the body turns attention away from the most important questions and that we cannot answer these ...
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Speech-driven embodied entrainment character system with pupillary response
Mechanical Engineering Journal, 2016 We have developed a speech-driven embodied entrainment character called “InterActor” that has functions of both speaker and listener for supporting human interaction and communication.
Yoshihiro SEJIMA +3 more
doaj +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source