Results 191 to 200 of about 308,636 (261)

Loss of Function of the <i>Zxdb</i> Gene Leads to a Decrease in the Decidualization Rate and Number of Pups Born in Mice by Affecting the Expression of the Cell Adhesion Molecules. [PDF]

Curr Issues Mol Biol
Tian Y, Zhang Y, Li M, Yin R, Ding P, Liang L, Chen B, Xu R, Chen H, Xu C, Chen S, Lu D.   +11 more
europepmc   +1 more source

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

Advanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao, Aiting Wang, Yue Xu, Wenxin Feng, Chunxiao Ma, Ziyi Wang, Wei Zhang, Wenqiong Su, Xiuying Xiao, Wei‐Qiang Gao, Xianting Ding, Li Li   +11 more
wiley   +1 more source

Inverted microscopy-based assessment reveals major maturation gap between denuded and non-denuded GV oocytes: A novel r-IVM approach. [PDF]

Turk J Obstet Gynecol
Peker N, Yücetürk A, Karaosmanoğlu Ö, Tığlı E, Elmas B, Aslan İÖ, Aksu Türan B, Tıraş B.   +7 more
europepmc   +1 more source

Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5‐Dependent RNA Demethylation

Advanced Science, EarlyView.
FT organoids reverse the aged phenotype of tendon cells, reinstating a fetal‐like state. This breakthrough establishes a potent cell source for tendon tissue engineering, effectively advancing regenerative medicine. ABSTRACT Adult tendon injuries pose a major clinical challenge due to limited self‐repair capacity, resulting in suboptimal regeneration ...
Tian Qin, Aini Pan, Zhuoning Miao, Yanyan Zhao, Xianan Mo, Heng Sun, Chunmei Fan, Junyu Guo, Bingbing Wu, Weiliang Shen, Qiangqiang Zheng, Jun Lu, Xi Jiang, Zi Yin, Xiao Chen   +14 more
wiley   +1 more source

Maternal-fetal attachment trajectories in IVF mothers during the first trimester: a prospective observational study. [PDF]

Arch Gynecol Obstet
Cheng X, Chen F, Huang H, Zhang F, Xu X.
europepmc   +1 more source

Tim1 Deficiency Mediates Gestational Hyperglycemia‐Related Syncytiotrophoblast Dysfunction and Fetal Growth Restriction

Advanced Science, EarlyView.
Hyperglycemia during pregnancy impairs the fusion of trophoblast cells into syncytiotrophoblasts, leading to fetal growth restriction. This impaired fusion is mediated by Tim1 downregulation via hyperglycemia‐induced ROS. Antioxidant therapy during pregnancy promotes syncytiotrophoblast formation by upregulating Tim1 expression, thus alleviating fetal ...
Junsen She, Rui Liu, Chen Fang, Shuyu Zhang, Yizhi Hu, Fei Guo, Yuhang Long, Mengzhen Ding, Haiyan Wu, Bokang Zhou, Zexin Yang, Ying Jiang, Jianzhong Sheng, Ling Gao, Hefeng Huang   +14 more
wiley   +1 more source

Impact of ovarian stimulation duration in GnRH antagonist protocols on the cumulative ongoing pregnancy rate in women with normal ovarian reserve: a cohort study. [PDF]

Reprod Biol Endocrinol
Cohen Aloro L, Saïs E, Becquart C, Thomas H, Souare F, Sellami I, Mayeur A, Hesters L, Grynberg M, Sonigo C.   +9 more
europepmc   +1 more source

Engineered Living Systems With Self‐Organizing Neural Networks: From Anatomy to Behavior and Gene Expression

Advanced Science, EarlyView.
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat, Laurie O'Neill, Léo Pio‐Lopez, Megan M. Sperry, Patrick Erickson, Tiffany Lin, Michael Levin   +6 more
wiley   +1 more source